...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Nature reviews Cancer >FRET-Based Semiconducting Polymer Dots for pH Sensing
【24h】

FRET-Based Semiconducting Polymer Dots for pH Sensing

机译：基于FRET的半导体聚合物点，用于pH感测

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Forster resonance energy transfer (FRET)-based polymer dots (Pdots), fabricated by semiconducting polymers and exhibiting excellent properties, have attracted much interest in the last decade, however, full polymer-dot-based pH sensors are seldom systematically exploited by researchers. In this work, we constructed a kind of blend polymer dot, utilizing poly[(9,9-dihexyl-9H-fluorene-2,7-vinylene)-co-(1-methoxy-4-(2-ethylhexyloxy)-2,5-phenylenevinylene)] (PFV) as the donor, poly[2,5-bis(3 ',7 '-dimethyloctyloxy)-1,4-phenylenevinylene] (BDMO-PPV) as the acceptor, and polysytrene graft EO functionalized with carboxy (PS-PEG-COOH) to generate surface carboxyl groups. This type of Pdot, based on the FRET process, was quite sensitive to pH value changes, especially low pH environments. When the pH value decreases down to 2 or 1, the fluorescence spectrum of Pdots-20% exhibit spectral and intensity changes at the same time, and fluorescence lifetime changes as well, which enables pH sensing applications. The sharpening of the emission peak at similar to 524 nm, along with the weakening and blue shifts of the emission band at similar to 573 nm, imply that the efficiency of the energy transfer between PFV and BDMO-PPV inside the Pdots-20% decreased due to polymer chain conformational changes. The time-resolved fluorescence measurements supported this suggestion. Pdots constructed by this strategy have great potential in many applications, such as industrial wastewater detection, in vitro and intracellular pH measurement, and DNA amplification and detection.
机译：孔口共振能量转移（FRET）基于半导体聚合物制造的基于聚合物点（PDOTS）并在过去十年中吸引了很多兴趣，然而，研究人员很少能够系统地利用全面的聚合物 - 点的pH传感器。在这项工作中，我们构建了一种混合聚合物点，利用聚[（9,9-二己基-9H-芴-2,7-乙烯基）-CO-（1-甲氧基-4-（2-乙基己氧基）-2 ，5-苯基乙烯基）]（PFV）作为供体，聚[2,5-双（3'，7'，7'-二偏羟基氧基）-1,4-苯乙烯]（BDMO-PPV）作为受体，官能化多电菌移植物EO用羧基（PS-PEG-COOH）产生表面羧基。这种类型的PDOT基于FRET过程对pH值变化非常敏感，尤其是低pH环境。当pH值降低至2或1时，PDOTS-20％的荧光光谱同时表现出光谱和强度变化，并且荧光寿命也变化，这使得pH感测应用能够。类似于524nm的发射峰的锐化，以及类似于573nm的发射带的弱化和蓝色偏移，意味着PFV和BDMO-PPV之间的能量传递的效率-20％降低由于聚合物链构象变化。分辨时分的荧光测量值支持了这一建议。由该策略构建的PDOT在许多应用中具有很大的潜力，例如工业废水检测，体外和细胞内pH测量和DNA扩增和检测。

著录项

  • 来源
    《Nature reviews Cancer》 |2019年第6期|共11页
  • 作者

    Ou Jiemei; Tan Huijun; Chen Zhong; Chen Xudong;

  • 作者单位

    Sun Yat Sen Univ Guangdong Engn Technol Res Ctr High Performance O Key Lab Polymer Composite &

    Sun Yat Sen Univ Guangdong Engn Technol Res Ctr High Performance O Key Lab Polymer Composite &

    Sun Yat Sen Univ Guangdong Engn Technol Res Ctr High Performance O Key Lab Polymer Composite &

    Sun Yat Sen Univ Guangdong Engn Technol Res Ctr High Performance O Key Lab Polymer Composite &

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 肿瘤学;
  • 关键词

    semiconducting polymers; polymer dots; FRET; pH sensing;

    机译：半导体聚合物;聚合物点;褶皱;pH感应;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号