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Should we eat more potassium to better control blood pressure in hypertension?

机译:我们应该多吃更多的钾来更好地控制高血压血压吗?

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摘要

Changes in lifestyle and nutrition are recommended as the first-step approach to the management of hypertension by all national and international guidelines. Today, when considering nutritional factors in hypertension, almost all the attention is focused on the reduction of salt intake to improve blood pressure (BP) control. Changes in potassium intake are only briefly evoked in guidelines. Few physicians actually think about proposing to eat more foods that are high in potassium (fruits, vegetables, nuts) to better control BP. Yet, during the last 40 years, increasing evidence has accumulated demonstrating that increasing potassium intake, either with food products or with supplements, is associated with significant reductions of both systolic and diastolic BP. The hypotensive effect of potassium is particularly marked in patients with hypertension and in subjects with a very high sodium intake, suggesting that potassium counterbalances the effects of sodium. In addition, several meta-analyses have now confirmed that high potassium intake reduces the risk of stroke by similar to 25%. Finally, increasing potassium in the diet may perhaps be beneficial for some renal patients, as post hoc analyses have suggested that a high potassium intake may retard the decline of renal function in patients with early chronic kidney disease (CKD) stages. However, high potassium intake may be risky and sometimes even dangerous in hypertensive patients with CKD stages 3-5, specifically diabetics. In this context, however, as the level of evidence remains low, more prospective clinical studies are needed. The goal of this review is to discuss the actual evidence that supports the recommendation to eat more potassium in order to better control BP in essential hypertension and to review the restrictions in CKD patients with hypertension.
机译:建议生活方式和营养的变化作为所有国家和国际指南管理高血压管理的第一步方法。如今,在考虑高血压营养因素时,几乎所有的关注都集中在减少盐摄入量以改善血压(BP)控制。钾摄入量的变化仅在指南中短暂诱发。很少有医生实际上考虑建议多吃钾(水果,蔬菜,螺母)的更多食物,以更好地控制BP。然而,在过去的40年中,增加证据积累了证明,随着食品或补充剂的增加,增加钾摄入量与收缩性和舒张性BP的显着降低有关。钾的低血压效果特别标记为高血压和具有非常高的钠钠的受试者,表明钾对钠的影响。此外,几次荟萃分析现已证实高钾摄入量降低了与25%相似的行程风险。最后,随着HOC分析表明,饮食中的饮食中的钾可能是有益的,因为HOC分析表明高钾摄入量可能会阻碍慢性肾病(CKD)阶段的患者肾功能下降。然而,高钾摄入可能是危险的,有时甚至在高血压患者中甚至危险的CKD阶段3-5,特别是糖尿病患者。然而,在这种情况下,随着证据水平仍然低,需要更多的前瞻性临床研究。本综述的目标是讨论支持该建议的实际证据,以便更好地控制必需高血压中的BP,并审查高血压患者的限制。

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