...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>New Journal of Chemistry >Layered double hydroxide decorated with Ag nanodendrites as an enhanced sensing platform for voltammetric determination of pyrazinamide
【24h】

Layered double hydroxide decorated with Ag nanodendrites as an enhanced sensing platform for voltammetric determination of pyrazinamide

机译：用Ag Nanodendrites装饰层状双氢氧化物作为增强的吡嗪酰胺的增强传感平台

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Herein, a sensitive electrochemical sensor for pyrazinamide (PZA) based on the electrodeposition of Ag nanodendrites (AgNDs) on a Zn-Al layered double hydroxide (LDH)-modified electrode was developed. The synthesized nanostructured materials were characterized by X-ray diffraction, Fourier transform IR spectroscopy, scanning electron microscopy, and energy dispersive X-ray analysis. In addition, voltammetric measurement of double layer capacitance was used to evaluate the real surface area of the AgND/LDH/GC electrode. Excellent electrocatalytic activity, high stability, anti-interference ability, and good reproducibility make this sensor a good candidate for trace PZA determination. Under optimal experimental conditions, the current response of the fabricated sensor obtained via differential pulse voltammetry increased linearly with PZA concentrations in the wide range from 9.0 x 10(-7) to 5.2 x 10(-4) mol L-1, and the detection limit was 7.2 x 10(-7) mol L-1 (S/N = 3). The proposed sensor was successfully applied for the determination of PZA in commercial pharmaceutical tablets, and the obtained results were comparable to those found by the official analytical protocols. Finally, the developed method was validated by the analysis of PZA spiked human serum and urine samples, and good recoveries were obtained in the range of 97.5-105.5%.
机译：这里，基于Zn-Al层状双氢氧化物（LDH）制氢化电极的Ag Nanodendrites（Agnds）电沉积的吡嗪酰胺（PZA）的敏感电化学传感器。通过X射线衍射，傅里叶变换IR光谱，扫描电子显微镜和能量分散X射线分析表征合成的纳米结构。此外，使用双层电容的伏安测量来评估AGND / LDH / GC电极的真实表面积。优异的电催化活性，高稳定性，抗干扰能力，良好的再现性使得该传感器成为痕量PZA测定的良好候选者。在最佳实验条件下，通过差分脉冲伏安法获得的制造传感器的电流响应随着PZA浓度的线性增加，宽范围为9.0×10（-7）至5.2×10（-4）摩尔L-1，以及检测限制为7.2×10（-7）mol L-1（S / N = 3）。所提出的传感器已成功应用于商业药物片中测定PZA，得到的结果与官方分析方案发现的结果相当。最后，通过对PZA尖刺人血清和尿液样品的分析验证了开发方法，获得了良好的回收率在97.5-105.5％的范围内。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号