5-Aminolevulinic Acid Fluorescence-Guided Resection of F-18-FET-PET Positive Tumor Beyond Gadolinium Enhancing Tumor Improves Survival in Glioblastoma

Muether Michael; Koch Raphael; Weckesser Matthias; Sporns Peter; Schwindt Wolfram; Stummer Walter

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5-Aminolevulinic Acid Fluorescence-Guided Resection of F-18-FET-PET Positive Tumor Beyond Gadolinium Enhancing Tumor Improves Survival in Glioblastoma

机译：5-氨基硫酸荧光酸荧光引导切除超越钆增强肿瘤的F-18-FET-PET阳性肿瘤的切除改善了胶质母细胞瘤的存活

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BACKGROUND: The value of early postoperative F-18-FET-PET in patients with glioblastoma (GBM) is unclear. Five-aminolevulinic acid (5-ALA) is used for fluorescence-guided resections in these patients and previous data suggest that fluorescence and F-18-FET-PET both demarcate larger tumor volumes than gadolinium enhanced magnet resonance imaging (MRI).

机译：背景：胶质母细胞瘤（GBM）患者术后早期F-18-FET-PET的值尚不清楚。这些患者中的五氨基乙酰丙酸（5-ALA）用于荧光导向切除，并且之前的数据表明，荧光和F-18-FET-PET两种肾上腺素增强磁体共振成像（MRI）划分较大的肿瘤体积。

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来源
《Neurosurgery》 |2019年第6期|共10页
作者
Muether Michael; Koch Raphael; Weckesser Matthias; Sporns Peter; Schwindt Wolfram; Stummer Walter;
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作者单位

Univ Hosp Munster Dept Neurosurg Albert Schweitzer Campus 1 D-48147 Munster Germany;

Univ Munster Inst Biostat &

Clin Res Munster Germany;

Univ Hosp Munster Dept Nucl Med Munster Germany;

Univ Hosp Munster Inst Clin Radiol Munster Germany;

Univ Hosp Munster Inst Clin Radiol Munster Germany;

Univ Hosp Munster Dept Neurosurg Albert Schweitzer Campus 1 D-48147 Munster Germany;

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原文格式 PDF
正文语种 eng
中图分类头部及神经外科学;
关键词
Aminolevulinic acid; Fluorescence; Gadolinium; Glioblastoma; Tumor burden; (18F)fluoroethyltyrosine;

机译：氨基乙酰丙酸;荧光;钆;胶质母细胞瘤;肿瘤负担;（18°F）氟乙基菌;

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1. 5-Aminolevulinic Acid Fluorescence-Guided Resection of F-18-FET-PET Positive Tumor Beyond Gadolinium Enhancing Tumor Improves Survival in Glioblastoma [J] . Muether Michael, Koch Raphael, Weckesser Matthias, Neurosurgery . 2019,第6期

机译：5-氨基硫酸荧光酸荧光引导切除超越钆增强肿瘤的F-18-FET-PET阳性肿瘤的切除改善了胶质母细胞瘤的存活
2. Impact of 5-aminolevulinic acid fluorescence-guided surgery on the extent of resection of meningiomas - With special regard to high-grade tumors [J] . J.F. Cornelius, P.J. Slotty, M.A. Kamp, Photodiagnosis and Photodynamic Therapy . 2014,第4期

机译：5-氨基乙酰丙酸荧光引导手术对脑膜瘤切除范围的影响-特别针对高级别肿瘤
3. Fluorescence-guided resection of metastatic brain tumors using a 5-aminolevulinic acid-induced protoporphyrin IX: pathological study [J] . Satoshi Utsuki, Norio Miyoshi, Hidehiro Oka, Brain Tumor Pathology . 2007,第2期

机译：使用5-氨基乙酰丙酸诱导的原卟啉IX的荧光导向切除转移性脑肿瘤：病理研究
4. Fluorescence-guided resection of intracranial VX2 tumor in a preclinical model using 5-aminolevulinic acid (ALA): Preliminary results [C] . A. Bogaards, A. Varma, E.H. Moriyama, Conference on Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XII Jan 25-26, 28, 2003 San Jose, California, USA . 2003

机译：在临床前模型中使用5-氨基乙酰丙酸（ALA）进行荧光引导的颅内VX2肿瘤切除术：初步结果
5. A Biomaterials Approach to Increasing the Persistence of Induced Neural Stem Cells in the Glioblastoma Tumor Resection Cavity [D] . Bomba, Hunter Nicole. 2021

机译：一种生物材料，以增加胶质母细胞瘤肿瘤切除腔中诱导神经干细胞持续性的方法
6. 5-Aminolevulinic Acid Multispectral Imaging for the Fluorescence-Guided Resection of Brain Tumors: A Prospective Observational Study [O] . Patra Charalampaki, Phileas Johannes Proskynitopoulos, Axel Heimann, 2020

机译：5-氨基纤维素酸多光谱成像用于脑肿瘤的荧光导向切除：一个前瞻性观察研究
7. 5-Aminolevulinic Acid Multispectral Imaging for the Fluorescence-Guided Resection of Brain Tumors: A Prospective Observational Study [O] . Patra Charalampaki, Phileas Johannes Proskynitopoulos, Axel Heimann, 2020

机译：5-氨基纤维素酸多光谱成像，用于脑肿瘤的荧光导向切除：一个前瞻性观察研究

5-Aminolevulinic Acid Fluorescence-Guided Resection of F-18-FET-PET Positive Tumor Beyond Gadolinium Enhancing Tumor Improves Survival in Glioblastoma

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