Surgical Decision Making From Image-Based Biophysical Modeling of Glioblastoma: Not Ready for Primetime

Amelot Aymeric; Deroulers Christophe; Badoual Mathilde; Polivka Marc; Adle-Biassette Homa; Houdart Emmanuel; Carpentier Antoine F.; Froelich Sebastien; Mandonnet Emmanuel

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Surgical Decision Making From Image-Based Biophysical Modeling of Glioblastoma: Not Ready for Primetime

机译：来自胶质母细胞瘤的基于图像的生物物理学建模的外科决策：尚未准备好primetime

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BACKGROUND: Biophysical modeling of glioma is gaining more interest for clinical practice. The most popular model describes aggressivity of tumor cells by two parameters: net proliferation rate (rho) and propensity to migrate (D). The ratio rho/D, which can be estimated from a single preoperative magnetic resonance imaging (MRI), characterizes tumor invasiveness profile (high rho/D: nodular; low rho/D: diffuse). A recent study reported, from a large series of glioblastoma multiforme (GBM) patients, that gross total resection (GTR) would improve survival only in patients with nodular tumors.

机译：背景：胶质瘤的生物物理建模在临床实践中获得更多兴趣。最受欢迎的模型描述了通过两个参数的肿瘤细胞的侵蚀性：净增殖率（RHO）和迁移（D）的倾向。与单一术前磁共振成像（MRI）估计的比率RHO / D表征肿瘤侵入性概况（高rho / d：结节;低rho / d：diffuse）。最近的一项研究报告，从大量的胶质母细胞瘤多形形母细胞瘤（GBM）患者，总分解（GTR）只会在结节性肿瘤患者中提高生存。

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来源
《Neurosurgery》 |2017年第5期|共7页
作者
Amelot Aymeric; Deroulers Christophe; Badoual Mathilde; Polivka Marc; Adle-Biassette Homa; Houdart Emmanuel; Carpentier Antoine F.; Froelich Sebastien; Mandonnet Emmanuel;
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作者单位

Hop Lariboisiere AP HP Serv Neurochirurg Paris France;

IMNC UMR8165 Orsay France;

IMNC UMR8165 Orsay France;

Hop Lariboisiere AP HP Serv Anatomopathol Paris France;

Hop Lariboisiere AP HP Serv Anatomopathol Paris France;

Hop Lariboisiere AP HP Serv Neuroradiol Paris France;

Hop Avicenne AP HP Serv Neurol Bobigny France;

Univ Paris 7 Diderot Paris France;

Hop Lariboisiere AP HP Serv Neurochirurg Paris France;

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原文格式 PDF
正文语种 eng
中图分类头部及神经外科学;
关键词
Glioblastoma; Biophysical modeling; Proliferation; Invasiveness; Surgery; Survival prognosis;

机译：胶质母细胞瘤;生物物理学建模;增殖;侵袭性;手术;生存预后;

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1. Letter: Surgical Decision Making From Image-Based Biophysical Modeling of Glioblastoma: Not Ready for Primetime [J] . Massey Susan Christine, Johnston Sandra K., Canoll Peter D., Neurosurgery . 2018,第1期

机译：字母：从胶质细胞瘤的基于图像的生物物理学建模制作的外科决策：尚未准备好primetime
2. Letter: Surgical Decision Making From Image-Based Biophysical Modeling of Glioblastoma: Not Ready for Primetime [J] . Massey Susan Christine, Johnston Sandra K., Canoll Peter D., Neurosurgery . 2018,第1期

机译：字母：从胶质细胞瘤的基于图像的生物物理学建模制作的外科决策：尚未准备好primetime
3. Surgical Decision Making From Image-Based Biophysical Modeling of Glioblastoma: Not Ready for Primetime [J] . Amelot Aymeric, Deroulers Christophe, Badoual Mathilde, Neurosurgery . 2017,第5期

机译：来自胶质母细胞瘤的基于图像的生物物理学建模的外科决策：尚未准备好primetime
4. Are Today's SDN Controllers Ready for Primetime? [C] . Stephen Mallon, Vincent Gramoli, Guillaume Jourjon IEEE Conference on Local Computer Networks . 2016

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5. Image-based remodeling: a framework for creating, visualizing, and editing image-based models. [D] . Colburn, R. Alex. 2014

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Surgical Decision Making From Image-Based Biophysical Modeling of Glioblastoma: Not Ready for Primetime

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