1,25-(OH)(2)D-3 protects Schwann cells against advanced glycation end products-induced apoptosis through PKA-NF-kappa B pathway

Xu Shiqing; Li Jing; Zhai Min; Yao Xiaoqi; Liu Honglin; Deng Tingting; Cai Hanqing; Zhang Wan; Zhang Wenjian; Lou Jinning; Peng Liang

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1,25-(OH)(2)D-3 protects Schwann cells against advanced glycation end products-induced apoptosis through PKA-NF-kappa B pathway

机译：1,25-（OH）（2）D-3通过PKA-NF-Kappa B途径保护Schwann细胞免受晚期糖化末端产物诱导的细胞凋亡

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摘要

Aims: To explore the effect and mechanism of 1, 25-(OH)(2)D-3 on Schwann cell apoptosis induced by advanced glycation end products.

机译：目的：探讨先进糖甘露糖末端产物诱导的施万细胞凋亡的1,25-（OH）（2）D-3的效果和机制。

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来源
《Life sciences》 |2019年第2019期|共10页
作者
Xu Shiqing; Li Jing; Zhai Min; Yao Xiaoqi; Liu Honglin; Deng Tingting; Cai Hanqing; Zhang Wan; Zhang Wenjian; Lou Jinning; Peng Liang;
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作者单位

China Japan Friendship Hosp Inst Clin Med Sci Beijing 100029 Peoples R China;

China Japan Friendship Hosp Dept Stomatol Beijing 100029 Peoples R China;

China Japan Friendship Hosp Inst Clin Med Sci Beijing 100029 Peoples R China;

China Japan Friendship Hosp Dept Ultrason Diag Beijing 100029 Peoples R China;

China Japan Friendship Hosp Inst Clin Med Sci Beijing 100029 Peoples R China;

China Japan Friendship Hosp Inst Clin Med Sci Beijing 100029 Peoples R China;

Jilin Univ Hosp 2 Dept Endocrinol Changchun 130041 Jilin Peoples R China;

China Japan Friendship Hosp Dept Clin Lab Beijing 100029 Peoples R China;

Suzhou Rely Biotech Co Ltd Suzhou 215103 Peoples R China;

Suzhou Rely Biotech Co Ltd Suzhou 215103 Peoples R China;

China Japan Friendship Hosp Inst Clin Med Sci Beijing 100029 Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类医药、卫生;
关键词
Diabetes; 1; 25-(OH)(2)D-3; Schwann cell; Apoptosis; PKA; NF-kappa B;

机译：糖尿病;1;25-（OH）（2）D-3;Schwann细胞;细胞凋亡;PKA;NF-Kappa B;

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专利

1. 1,25-(OH)(2)D-3 protects Schwann cells against advanced glycation end products-induced apoptosis through PKA-NF-kappa B pathway [J] . Xu Shiqing, Li Jing, Zhai Min, Life sciences . 2019,第期

机译：1,25-（OH）（2）D-3通过PKA-NF-Kappa B途径保护Schwann细胞免受晚期糖化末端产物诱导的细胞凋亡
2. Advanced glycation end products-induced apoptosis attenuated by PPARdelta activation and epigallocatechin gallate through NF-kappaB pathway in human embryonic kidney cells and human mesangial cells. [J] . Liang YJ, Jian JH, Liu YC, Diabetes/metabolism research and reviews . 2010,第5期

机译：晚期糖基化终产物诱导的凋亡通过人胚肾细胞和肾小球系膜细胞中的PPARδ激活和表没食子儿茶素没食子酸酯通过NF-κB途径而减弱。
3. The C-terminal tails of 4,4'-diphenylmethane-bis(methyl) carbamate are essential for binding to receptor for advanced glycation end products to attenuate advanced glycation end products-induced inflammation and apoptosis responses in human umbilical vein endothelial cells [J] . Journal of Pharmacy and Pharmacology . 2016,第1期

机译：4,4'-二苯甲烷-氨基甲酸双（甲基）氨基甲酸酯的C末端尾对于与晚期糖基化终产物的受体结合以减弱晚期糖基化终产物诱导的人脐静脉内皮细胞炎症和凋亡反应至关重要
4. Ugonin K induces Cell Cycle Arrest and Apoptosis through Reactive oxygen species/Apoptosis Signal Pathway in Human Skin Cancer Cells [C] . Leong-Perng Chan, Tzung-Han Chou, Guey-Horng Wang, International Conference on Manufacturing Science and Engineering . 2013

机译：Ugonin K通过在人体皮肤癌细胞中的活性氧物质/凋亡信号途径诱导细胞周期停滞和细胞凋亡
5. Receptor for advanced glycation endproducts mediates allergic airway inflammation via group 2 innate lymphoid cells. [D] . Oczypok, Elizabeth Ann. 2015

机译：晚期糖基化终产物的受体通过第2组先天淋巴样细胞介导过敏性气道炎症。
6. Ghrelin protects human umbilical vein endothelial cells against advanced glycation end products-induced apoptosis via NO/cGMP signaling [O] . Pengjie Li, Ying Liu, Ying Xiang, 2015

机译：Ghrelin通过NO / cGMP信号传导保护人脐静脉内皮细胞免于晚期糖基化终产物诱导的细胞凋亡
7. Mitochondrial Pathway Is Involved in Advanced Glycation End Products-Induced Apoptosis of Rabbit Annulus Fibrosus Cells [O] . Yiqiang Hu, Zengwu Shao, Xianyi Cai, 2019

机译：线粒体途径参与先进的糖化末端产物 - 诱导兔环状纤维细胞的凋亡

1,25-(OH)(2)D-3 protects Schwann cells against advanced glycation end products-induced apoptosis through PKA-NF-kappa B pathway

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