Allicin alleviated learning and memory deficits caused by lead exposure at developmental stage

Cai Shizhong; Liu Jun; Shi Xiaoyan; Hu Shousen; Zhao Lina

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Allicin alleviated learning and memory deficits caused by lead exposure at developmental stage

机译：Allicin缓解了在发育阶段的铅曝光引起的学习和记忆缺陷

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Aims: It is a promising approach to search the therapeutic strategies for treating lead (Pb) toxicity. Allicin, a natural compound extracted from Allium sativum (garlic), has been reported to have many beneficially biological properties. In this study, we investigated the protective effects of allicin on learning and memory function of rats exposed by lead acetate at developmental stage.

机译：目的：这是一个有望的方法，可以搜索治疗铅（Pb）毒性的治疗策略。据报道，来自Allium Sativum（大蒜）中提取的天然化合物，已举报具有许多有利的生物学性质。在这项研究中，我们研究了AlliCIN对发育阶段铅暴露的大鼠学习和记忆功能的保护作用。

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来源
《Life sciences》 |2019年第2019期|共7页
作者
Cai Shizhong; Liu Jun; Shi Xiaoyan; Hu Shousen; Zhao Lina;
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作者单位

Soochow Univ Chidrens Hosp Dept Child &

Adolescent Healthcare 92 Zhongnan Rd Suzhou 215021;

Soochow Univ Affiliated Hosp 1 Collaborat Innovat Ctr Haematol Minist Hlth Jiangsu Inst Haematol;

Soochow Univ Childrens Hosp Dept Neurol Suzhou 215021 Jiangsu Peoples R China;

Zhengzhou Univ Affiliated Hosp 1 Dept Otolaryngol Head &

Neck Surg Zhengzhou 450052 Henan;

Soochow Univ Affiliated Hosp 1 Key Lab Clin Immunol Jiangsu Prov Dept Lab Med 188 Shizi Ave;

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原文格式 PDF
正文语种 eng
中图分类医药、卫生;
关键词
Allicin; Lead acetate; Learning and memory deficit; Astrocyte; EGFR/ERK signaling;

机译：AlliCIN;醋酸铅;学习和记忆缺陷;星形胶质细胞;EGFR / ERK信号;

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专利

1. Allicin alleviated learning and memory deficits caused by lead exposure at developmental stage [J] . Cai Shizhong, Liu Jun, Shi Xiaoyan, Life sciences . 2019,第期

机译：Allicin缓解了在发育阶段的铅曝光引起的学习和记忆缺陷
2. Maternal administration of melatonin prevents spatial learning and memory deficits induced by developmental ethanol and lead co-exposure [J] . Soleimani Elham, Goudarzi Iran, Abrari Kataneh, Physiology & behavior . 2017,第期

机译：母体施用褪黑激素可防止发育乙醇诱导的空间学习和记忆缺陷和铅共曝光
3. Lead exposure through gestation-only caused long-term learning/memory deficits in young adult offspring. [J] . Yang Y, Ma Y, Ni L, Experimental Neurology . 2003,第1期

机译：仅通过妊娠接触铅会导致成年后代的长期学习/记忆缺陷。
4. Thinner Exposure and Memory and Learning Deficits [C] . Victor Nedzvetskii, Svetlana Kyrychenko, Giyasettin Baydas Environmental and food safety and security for south-east Europe and Ukraine. . 2011

机译：较弱的接触和记忆与学习不足
5. Exposure to ethanol during the rat brain growth spurt: Characterizing the learning and memory deficits using variations of the Morris water maze. [D] . Girard, Todd Alexander. 2002

机译：在大鼠大脑生长过程中暴露于乙醇：使用莫里斯水迷宫的变化来表征学习和记忆障碍。
6. Effects of Low Level Lead Exposure on Associative Learning and Memory in the Rat: Influences of Sex and Developmental Timing Of Exposure [O] . D.W. Anderson, W. Mettil, J.S. Schneider -1

机译：低水平铅暴露对大鼠联想学习和记忆的影响：性别和暴露发育时间的影响
7. Dietary intake of magnesium-l-threonate alleviates memory deficits induced by developmental lead exposure in rats [O] . Zhi-Yi Lou, Weiheng Chen, Wei-zhen Xue, 2017

机译：镁 - L-苏氨酸的饮食摄入量减轻了大鼠发育铅暴露引起的记忆缺陷

Allicin alleviated learning and memory deficits caused by lead exposure at developmental stage

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