Decreased reactive oxygen species production and NOX1, NOX2, NOX4 expressions contribute to hyporeactivity to phenylephrine in aortas of pregnant SHR

Troiano J. A.; Potje S. R.; Graton M. E.; Cavalari P.; Pereira A. A. F.; Vale G. T.; Nakamune A. C. M. S.; Sumida D. H.; Tirapelli C. R.; Antoniali C.

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Decreased reactive oxygen species production and NOX1, NOX2, NOX4 expressions contribute to hyporeactivity to phenylephrine in aortas of pregnant SHR

机译：反应性氧物种产量和NOx1，NOX2，NOX4表达有助于怀孕SHR的主动脉染色中对苯甲酸的高钙性

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Aims: We determined whether decreased reactive oxygen species (ROS) production in the aorta of pregnant spontaneously hypertensive rats (SHR) resulted in increased nitric oxide (NO) bioavailability and hyporeactivity to phenylephrine (PE).

机译：目的：我们确定了怀孕的主动脉的反应性氧物种（ROS）产生是否可自发的高血压大鼠（SHR）增加，导致一氧化氮增加（NO）生物利用度和对苯酚肾上腺素的高恶性（PE）。

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来源
《Life sciences》 |2016年第1期|共7页
作者
Troiano J. A.; Potje S. R.; Graton M. E.; Cavalari P.; Pereira A. A. F.; Vale G. T.; Nakamune A. C. M. S.; Sumida D. H.; Tirapelli C. R.; Antoniali C.;
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作者单位

SBFis Programa Posgrad Multictr Ciencias Fisiol Rio De Janeiro Brazil;

SBFis Programa Posgrad Multictr Ciencias Fisiol Rio De Janeiro Brazil;

SBFis Programa Posgrad Multictr Ciencias Fisiol Rio De Janeiro Brazil;

UNESP Univ Estadual Paulista Sch Dent Aracatuba Dept Basic Sci Sao Paulo Brazil;

SBFis Programa Posgrad Multictr Ciencias Fisiol Rio De Janeiro Brazil;

Univ Sao Paulo Coll Nursing Ribeirao Preto Dept Psychiat Nursing &

Human Sci BR-09500900 Sao;

SBFis Programa Posgrad Multictr Ciencias Fisiol Rio De Janeiro Brazil;

SBFis Programa Posgrad Multictr Ciencias Fisiol Rio De Janeiro Brazil;

Univ Sao Paulo Coll Nursing Ribeirao Preto Dept Psychiat Nursing &

Human Sci BR-09500900 Sao;

SBFis Programa Posgrad Multictr Ciencias Fisiol Rio De Janeiro Brazil;

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原文格式 PDF
正文语种 eng
中图分类医药、卫生;
关键词
Aorta; Hypertension; Hyporeactivity; Pregnancy; Reactive oxygen species;

机译：主动脉;高血压;高酸;怀孕;活性氧;

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专利

1. Decreased reactive oxygen species production and NOX1, NOX2, NOX4 expressions contribute to hyporeactivity to phenylephrine in aortas of pregnant SHR [J] . Troiano J. A., Potje S. R., Graton M. E., Life sciences . 2016,第1期

机译：反应性氧物种产量和NOx1，NOX2，NOX4表达有助于怀孕SHR的主动脉染色中对苯甲酸的高钙性
2. Differential regulation of Nox1, Nox2 and Nox4 in vascular smooth muscle cells from WKY and SHR. [J] . Briones AM, Tabet F, Callera GE, Journal of the American Society of Hypertension : . 2011,第3期

机译：NOx1，NOx2和NOx4的差异调节来自WKY和SHR的血管平滑肌细胞。
3. Activation of NOX2 by the stimulation of ionotropic and metabotropic glutamate receptors contributes to glutamate neurotoxicity in vivo through the production of reactive oxygen species and calpain activation. [J] . Guemez Gamboa A, Estrada Sanchez AM, Montiel T, Journal of Neuropathology and Experimental Neurology: Official Journal of the American Association of Neuropathologists, Inc . 2011,第11期

机译：通过刺激离子型和代谢型谷氨酸受体来激活NOX2，可通过产生活性氧和钙蛋白酶激活来促进体内谷氨酸神经毒性。
4. Increased trans-endothelial cells permeability induced by oxidized lipoprotein(a) relates to reactive oxygen species generation and desmogleins expression [C] . Zuo Wang, Jian Yang, Xiao-lei Zhang, World Congress on Medical Physics and Biomedical Engineering . 2013

机译：氧化脂蛋白（a）诱导的跨内皮细胞通透性增加与活性氧的产生和桥粒糖蛋白的表达有关
5. The effects of cadmium and 1,2-dhATQ on reactive oxygen species (ROS) production, photosynthesis and gene expression in Lemna gibba (duckweed). [D] . Lees, Hazel Anne. 2006

机译：镉和1,2-dhATQ对浮萍中活性氧（ROS）的产生，光合作用和基因表达的影响。
6. Increasing UCP2 expression and decreasing NOX1/4 expression maintain chondrocyte phenotype by reducing reactive oxygen species production [O] . Yansong Miao, Yuefu Dong, Ping Huang, 2017

机译：增加UCP2表达并减少NOX1 / 4表达可通过减少活性氧的产生来维持软骨细胞表型
7. Decreased reactive oxygen species production and NOX1, NOX2, NOX4 expressions contribute to hyporeactivity to phenylephrine in aortas of pregnant SHR [O] . Troiano J.A., Potje S.R., Graton M.E., 2016

机译：孕妇SHR主动脉中活性氧的产生减少以及NOX1，NOX2，NOX4的表达对去氧肾上腺素的反应性降低
8. Hypoxia Inducible Factor 1 (HIF-1) Activation in U87 Glioma Cells Involves a Decrease in Reactive Oxygen Species Production and Protein Kinase C Activity [R] . Forbes, R. A. 1998

机译：U87神经胶质瘤细胞中的缺氧诱导因子1（HIF-1）活化涉及活性氧生成和蛋白激酶C活性的降低

Decreased reactive oxygen species production and NOX1, NOX2, NOX4 expressions contribute to hyporeactivity to phenylephrine in aortas of pregnant SHR

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