(-)-Epigallocatechin-3-gallate alleviates doxorubicin-induced cardiotoxicity in sarcoma 180 tumor-bearing mice

Yao Yu-Fei; Liu Xiang; Li Wen-Juan; Shi Zi-Wei; Yan Yu-Xin; Wang Le-Feng; Chen Ming; Xie Ming-Yong

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(-)-Epigallocatechin-3-gallate alleviates doxorubicin-induced cardiotoxicity in sarcoma 180 tumor-bearing mice

机译：（ - ） - Epigallocatechin-3-gallate在肉瘤180肿瘤患者中缓解了多柔比星诱导的心脏毒性

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摘要

Aims: (-)-Epigallocatechin-3-gallate (EGCG), a major green tea polyphenol compound, plays an important role in the prevention of cardiovascular disease and cancer. The present study aimed to investigate the effects of EGCG on doxorubicin (DOX)-induced cardiotoxicity in Sarcoma 180 (S180) tumor-bearing mice.

机译：目的：（ - ） - Epigallocatechin-3-gallate（EGCG），一种主要的绿茶多酚化合物，在预防心血管疾病和癌症中起重要作用。本研究旨在探讨EGCG对多柔比星（DOX）的影响 - 诱导肉瘤180（S180）肿瘤小鼠的心毒性。

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来源
《Life sciences》 |2017年第2017期|共9页
作者
Yao Yu-Fei; Liu Xiang; Li Wen-Juan; Shi Zi-Wei; Yan Yu-Xin; Wang Le-Feng; Chen Ming; Xie Ming-Yong;
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作者单位

Chinese Liberat Army 94 Hosp 1028 Jinggangshan Ave Nanchang 330000 Jiangxi Peoples R China;

Nanchang Univ Sch Basic Med Sci 999 Xuefu Rd Nanchang 330031 Jiangxi Peoples R China;

Nanchang Univ State Key Lab Food Sci &

Technol 235 Nanjing East Rd Nanchang 330047 Jiangxi;

Nanchang Univ State Key Lab Food Sci &

Technol 235 Nanjing East Rd Nanchang 330047 Jiangxi;

Nanchang Univ Sch Basic Med Sci 999 Xuefu Rd Nanchang 330031 Jiangxi Peoples R China;

Nanchang Univ Sch Basic Med Sci 999 Xuefu Rd Nanchang 330031 Jiangxi Peoples R China;

Nanchang Univ Sch Basic Med Sci 999 Xuefu Rd Nanchang 330031 Jiangxi Peoples R China;

Nanchang Univ State Key Lab Food Sci &

Technol 235 Nanjing East Rd Nanchang 330047 Jiangxi;

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原文格式 PDF
正文语种 eng
中图分类医药、卫生;
关键词
(-)-Epigallocatechin-3-gallate; Doxorubicin; Cardiotoxicity; Reactive oxygen species;

机译：（ - ） - Epigallocatechin-3-gallate;多柔比星;心脏毒性;反应性氧;

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专利

1. (-)-Epigallocatechin-3-gallate alleviates doxorubicin-induced cardiotoxicity in sarcoma 180 tumor-bearing mice [J] . Yao Yu-Fei, Liu Xiang, Li Wen-Juan, Life sciences . 2017,第期

机译：（ - ） - Epigallocatechin-3-gallate在肉瘤180肿瘤患者中缓解了多柔比星诱导的心脏毒性
2. Baicalein alleviates doxorubicin-induced cardiotoxicity via suppression of myocardial oxidative stress and apoptosis in mice [J] . Sahu Bidya Dhar, Kumar Jerald Mahesh, Kuncha Madhusudana, Life sciences . 2016,第1期

机译：Baicalein通过抑制小鼠心肌氧化应激和细胞凋亡来减轻多柔比蛋白诱导的心脏毒性
3. Doxorubicin-loaded polymeric micelles based on bioactive polypeptides: Suppress invasion of melanoma cells and alleviate doxorubicin-induced cardiotoxicity [J] . Wang Qi-Ming, Gao Zhonggao, Liu Shan, Journal of Controlled Release: Official Journal of the Controlled Release Society . 2015,第Null期

机译：基于生物活性多肽的阿霉素负载聚合物胶束：抑制黑素瘤细胞的侵袭并减轻阿霉素诱导的心脏毒性
4. Study on S180 and H22 Tumor suppressor and inducing apoptosis on tumor-bearing mice by ground beetle's fibrinolytic Protein [C] . Lei Yu, Ya-Li Han IT in Medicine and Education (ITME), 2011 International Symposium on . 2011

机译：甲虫的纤溶蛋白抑制S180和H22肿瘤并诱导荷瘤小鼠凋亡的研究
5. Role of cytochrome P450 enzymes in the pathogenesis of cardiac hypertrophy and doxorubicin-induced cardiotoxicity. [D] . Zordoky, Beshay Nazmy Mounir. 2012

机译：细胞色素P450酶在心脏肥大和阿霉素引起的心脏毒性的发病机理中的作用。
6. The improved antitumor efficacy of continuous intratumoral chemotherapy with cisplatin-loaded implants for the treatment of sarcoma 180 tumor-bearing mice [O] . Li Gao, Shang Cai, Awei Cai, 2019

机译：负载顺铂植入物的连续瘤内化学疗法治疗荷瘤肉瘤180小鼠的抗肿瘤疗效提高
7. The improved antitumor efficacy of continuous intratumoral chemotherapy with cisplatin-loaded implants for the treatment of sarcoma 180 tumor-bearing mice [O] . Li Gao, Shang Cai, Awei Cai, 2019

机译：连续肿瘤植入物与顺铂植入物治疗Sarcoma 180肿瘤小鼠的改善抗肿瘤疗效

(-)-Epigallocatechin-3-gallate alleviates doxorubicin-induced cardiotoxicity in sarcoma 180 tumor-bearing mice

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