Arylnaphthalene lactone analogues: synthesis and development as excellent biological candidates for future drug discovery

Zhao Chuang; Rakesh K. P.; Mumtaz Saira; Moku Balakrishna; Asiri Abdullah M.; Marwani Hadi M.; Manukumar H. M.; Qin Hua-Li

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Arylnaphthalene lactone analogues: synthesis and development as excellent biological candidates for future drug discovery

机译：芳基萘内酯类似物：合成和开发作为未来药物发现的优秀生物学候选者

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Arylnaphthalene lactones are natural products extracted from a wide range of different parts of plants. The progressing interest in the synthesis of these compounds is due to their significant biological activities, which have made them potential candidates in drug discovery and development. This review mainly covers recent developments in the synthesis and biological applications of arylnaphthalene lactone analogs.

机译：芳基萘内酯是从各种不同部分植物中提取的天然产物。这些化合物合成的进展兴趣是由于它们的显着生物活性，这使得它们在药物发现和发育中成为潜在的候选人。本综述主要涵盖芳基萘内酯类似物的合成和生物学应用的最新发展。

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《RSC Advances》 |2018年第17期|共16页
作者
Zhao Chuang; Rakesh K. P.; Mumtaz Saira; Moku Balakrishna; Asiri Abdullah M.; Marwani Hadi M.; Manukumar H. M.; Qin Hua-Li;
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作者单位

Wuhan Univ Technol Sch Chem Chem Engn &

Life Sci Dept Pharmaceut Engn 205 Luoshi Rd Wuhan 430073 Hubei Peoples R China;

Wuhan Univ Technol Sch Chem Chem Engn &

Life Sci Dept Pharmaceut Engn 205 Luoshi Rd Wuhan 430073 Hubei Peoples R China;

Wuhan Univ Technol Sch Chem Chem Engn &

Life Sci Dept Pharmaceut Engn 205 Luoshi Rd Wuhan 430073 Hubei Peoples R China;

Wuhan Univ Technol Sch Chem Chem Engn &

Life Sci Dept Pharmaceut Engn 205 Luoshi Rd Wuhan 430073 Hubei Peoples R China;

King Abdulaziz Univ Dept Chem Fac Sci Jeddah 21589 Saudi Arabia;

King Abdulaziz Univ Dept Chem Fac Sci Jeddah 21589 Saudi Arabia;

Univ Mysore Dept Studies Biotechnol Mysuru 570006 Karnataka India;

Wuhan Univ Technol Sch Chem Chem Engn &

Life Sci Dept Pharmaceut Engn 205 Luoshi Rd Wuhan 430073 Hubei Peoples R China;

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正文语种 eng
中图分类化学;
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1. Arylnaphthalene lactone analogues: synthesis and development as excellent biological candidates for future drug discovery [J] . Zhao Chuang, Rakesh K. P., Mumtaz Saira, RSC Advances . 2018,第17期

机译：芳基萘内酯类似物：合成和开发作为未来药物发现的优秀生物学候选者
2. Arylnaphthalene lactone analogues: synthesis and development as excellent biological candidates for future drug discovery [J] . Chuang Zhao, K. P. Rakesh, Saira Mumtaz, RSC Advances . 2018,第17期

机译：芳基萘内酯类似物：合成和开发为未来药物开发的优秀生物候选物
3. Recent efforts toward the development of peptide secondary structure mimetics at Molecumetics Ltd. for the discoveries of new drug candidates utilizing combinatorial chemistry with solid phase synthesis are described [J] . J. Sharon S. Sarantopoulos W. Den C. Y. Kao C. M. Baecher-Allan K. E. Santora S. R. Sompuram S. Petersen-Mahrt B. R. Williams Combinatorial Chemistry & High Throughput Screening . 2000,第3期

机译：描述了Molecumetics Ltd.为开发肽二级结构模拟物而进行的最新努力，以利用组合化学与固相合成技术发现新的候选药物
4. Discovery of drug candidates acting on the molecular residence in biological systems [C] . Akira Asai 日本化学会春季年会講演予稿集 . 2018

机译：发现生物系统分子住宅的药物候选者
5. Part I. Total synthesis of panaxytriol and its biological evaluations in drug discovery program. Part II. Development of Homo-Robinson annulation and its synthetic application to guanacastepene A. Part III. Progress towards the total synthesis of xestocyclamine A. [D] . Yun, Heedong. 2006

机译：第一部分：人参三醇的全合成及其在药物发现程序中的生物学评估。第二部分Homo-Robinson环空技术的发展及其在鸟粪甲中的合成应用。第三部分。全合成xestocyclamine A的进展。
6. Novel Pieces for the Emerging Picture of Sulfoximines in Drug Discovery: Synthesis and Evaluation of Sulfoximine Analogues of Marketed Drugs and Advanced Clinical Candidates [O] . Dr. Juan Alberto Sirvent, Dr. Ulrich Lücking -1

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Arylnaphthalene lactone analogues: synthesis and development as excellent biological candidates for future drug discovery

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