Physico-chemical studies of resveratrol, methyl-jasmonate and cyclodextrin interactions: an approach to resveratrol bioproduction optimization

Oliva E.; Mathiron D.; Bertaut E.; Landy D.; Cailleu D.; Pilard S.; Clement C.; Courot E.; Bonnet V.; Djedaini-Pilard F.

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Physico-chemical studies of resveratrol, methyl-jasmonate and cyclodextrin interactions: an approach to resveratrol bioproduction optimization

机译：白藜芦醇，甲基 - 己酸酯和环糊精相互作用的物理化学研究：白藜芦醇生物生产优化的方法

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trans-Resveratrol (RSV) is a natural phenolic molecule of the stilbene family known for its anti-oxidant properties in the field of nutraceuticals and cosmetics. Its production by grapevine cell suspensions is induced by the addition to the culture medium of elicitor compounds, methyl jasmonate (MeJA) and cyclodextrins (CDs). Physico-chemical studies were performed to understand the mechanism of action of CDs on this bioproduction of RSV. Inclusion complexes of RSV in CDs were first observed and then interactions with MeJA were identified using various analytical techniques such as UV and nuclear magnetic resonance (NMR) spectroscopies, mass spectrometry (MS) and isothermal titration calorimetry (ITC).

机译：转霉（RSV）是斯蒂替斯科族的天然酚类分子，其抗氧化特性在营养素和化妆品领域。通过葡萄细胞悬浮液的产量通过引导剂化合物的培养基，茉莉甲酸甲酯（MEJA）和环糊精（CDS）的添加来诱导。进行物理化学研究以了解CDS对这种RSV的这种作用的作用机制。首先观察到CDS中RSV的包合物，然后使用各种分析技术，例如UV和核磁共振（NMR）光谱，质谱（MS）和等温滴定热量（ITC）来鉴定与MEJA的相互作用。

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《RSC Advances》 |2018年第3期|共11页
作者
Oliva E.; Mathiron D.; Bertaut E.; Landy D.; Cailleu D.; Pilard S.; Clement C.; Courot E.; Bonnet V.; Djedaini-Pilard F.;
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作者单位

Univ Picardie Jules Verne LG2A UMR 7378 CNRS Lab Glycochim Antimicrobiens &

Agroresources 33 Rue Saint Leu F-80039 Amiens France;

Univ Picardie Jules Verne Plateforme Analyt 33 Rue Saint Leu F-80039 Amiens France;

ULCO UCEIV EA 4492 F-59140 Dunkerque France;

ULCO UCEIV EA 4492 F-59140 Dunkerque France;

Univ Picardie Jules Verne Plateforme Analyt 33 Rue Saint Leu F-80039 Amiens France;

Univ Picardie Jules Verne Plateforme Analyt 33 Rue Saint Leu F-80039 Amiens France;

Univ Reims UFR Sci URVVC EA 4707 BP 1039 Moulin Housse F-51687 Reims France;

Univ Reims UFR Sci URVVC EA 4707 BP 1039 Moulin Housse F-51687 Reims France;

Univ Picardie Jules Verne LG2A UMR 7378 CNRS Lab Glycochim Antimicrobiens &

Agroresources 33 Rue Saint Leu F-80039 Amiens France;

Univ Picardie Jules Verne LG2A UMR 7378 CNRS Lab Glycochim Antimicrobiens &

Agroresources 33 Rue Saint Leu F-80039 Amiens France;

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正文语种 eng
中图分类化学;
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1. Physico-chemical studies of resveratrol, methyl-jasmonate and cyclodextrin interactions: an approach to resveratrol bioproduction optimization [J] . Oliva E., Mathiron D., Bertaut E., RSC Advances . 2018,第3期

机译：白藜芦醇，甲基 - 己酸酯和环糊精相互作用的物理化学研究：白藜芦醇生物生产优化的方法
2. From guest to ligand - A study on the competing interactions of antitumor drug resveratrol with β-cyclodextrin and bovine serum albumin [J] . Li X., Li H., Liu M., Thermochimica Acta: An International Journal Concerned with the Broader Aspects of Thermochemistry and Its Applications to Chemical Problems . 2011,第1a2期

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3. Microcalorimetric and spectrographic studies on host-guest interactions of α-, β-, γ- And Mβ-cyclodextrin with resveratrol [J] . Li H., Xu X., Liu M., Thermochimica Acta: An International Journal Concerned with the Broader Aspects of Thermochemistry and Its Applications to Chemical Problems . 2010,第1a2期

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7. A multi-scale approach to study biochemical and biophysical aspects of resveratrol on diesel exhaust particle-human primary lung cell interaction [O] . Wei Zhang, Qifei Li, Mingjie Tang, 2019

机译：一种多规模方法，用于研究白藜芦醇生物化学和生物物理方面对柴油机 - 人原发性肺细胞相互作用的生化和生物物理方面
8. Physico-Chemical Methods for the Study of Polycyclic Aromatic Hydrocarbon Carcinogen-DNA Interactions: Progress Report, 3/1/85 to 2/29/88 [R] . 1988

机译：用于研究多环芳烃致癌物-DNa相互作用的物理化学方法：进展报告，3/1/85至2/29/88

Physico-chemical studies of resveratrol, methyl-jasmonate and cyclodextrin interactions: an approach to resveratrol bioproduction optimization

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