Lipofection with estrone-based luminophores featuring aggregation-induced emission properties

Riebe Steffen; Zimmermann Alexander; Koch Johannes; Vallet Cecilia; Knauer Shirley K.; Sowa Andrea; Wolper Christoph; Voskuhl Jens

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Lipofection with estrone-based luminophores featuring aggregation-induced emission properties

机译：利用基于雌激素的荧光细胞的脂质引起的聚集诱导的发射特性

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In this communication we present the use of a novel class of luminophores with aggregation-induced emission (AIE) properties based on the steroid estrone. These molecules were equipped with cationic residues yielding amphiphiles suitable for lipofection. To this end, self-assembled luminescent structures were formed in aqueous media and mixed with a red-fluorescent protein expressing plasmid, yielding lipoplexes with increased emission intensity. These luminescent lipoplexes were able to efficiently transfect HeLa and HEK 293T cells and were able to be tracked due to the aggregation induced-emission properties.

机译：在该通信中，我们介绍了基于类固醇雌激素的聚集诱导的发射（AIE）性能的新型发光体。这些分子配备有阳离子残留物，得到适合于脂质的两亲物。为此，在含水介质中形成自组装的发光结构，并与表达质粒的红荧光蛋白混合，产生具有增加的发射强度的脂肪量。这些发光脂质体能够有效地转染HeLa和Hek 293T细胞，并且能够由于聚集诱导性排放性能被跟踪。

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《RSC Advances》 |2020年第33期|共5页
作者
Riebe Steffen; Zimmermann Alexander; Koch Johannes; Vallet Cecilia; Knauer Shirley K.; Sowa Andrea; Wolper Christoph; Voskuhl Jens;
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Univ Duisburg Essen Inst Organ Chem Univ Str 7 D-45141 Essen Germany;

Univ Duisburg Essen Inst Organ Chem Univ Str 7 D-45141 Essen Germany;

Univ Duisburg Essen Ctr Med Biotechnol ZMB ICCE Univ Str 2 D-45141 Essen Germany;

Univ Duisburg Essen Ctr Med Biotechnol ZMB Dept Mol Biol 2 D-45117 Essen Germany;

Univ Duisburg Essen Ctr Med Biotechnol ZMB Dept Mol Biol 2 D-45117 Essen Germany;

Univ Duisburg Essen Inst Organ Chem Univ Str 7 D-45141 Essen Germany;

Univ Duisburg Essen Inst Inorgan Chem Univ Str 5-7 D-45117 Essen Germany;

Univ Duisburg Essen Inst Organ Chem Univ Str 7 D-45141 Essen Germany;

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正文语种 eng
中图分类化学;
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1. Lipofection with estrone-based luminophores featuring aggregation-induced emission properties [J] . Riebe Steffen, Zimmermann Alexander, Koch Johannes, RSC Advances . 2020,第33期

机译：利用基于雌激素的荧光细胞的脂质引起的聚集诱导的发射特性
2. Twisted Donor-Acceptor Cruciform Luminophores Possessing Substituent-Dependent Properties of Aggregation-Induced Emission and Mechanofluorochromism [J] . Wang Yonghui, Xu Defang, Gao Huaizhi, The journal of physical chemistry, C. Nanomaterials and interfaces . 2018,第4期

机译：扭曲的供体受体甲状发光体，具有聚集诱导的发射和机械荧光变性的取代基依赖性性质
3. Mechanofluorochromic properties of aggregation-induced emission-active tetraphenylethene-containing cruciform luminophores [J] . Wang Yonghui, Xu Defang, Gao Huaizhi, Dyes and Pigments . 2018,第期

机译：聚集诱导的发光活性四苯基乙二乙烯硫胺发光体的机械荧光变性特性
4. Laser-ablative synthesis of aggregation-induced enhanced emission luminophore dyes in aqueous solutions [C] . C.-K. Lim, A. A. Popov, G. Tselikov, Synthesis and Photonics of Nanoscale Materials XVI . 2019

机译：水溶液中聚集诱导的增强发射发光体染料的激光烧蚀合成
5. Amphiphilic Luminogenic Materials with Aggregation-Induced Emission Features : Synthesis, Properties and Biological Applications. [D] . Chen, Yilong. 2014

机译：具有聚集诱导发射特性的两亲发光材料：合成，性质和生物应用。
6. Achieving very bright mechanoluminescence from purely organic luminophores with aggregation-induced emission by crystal design [O] . Bingjia Xu, Wenlang Li, Jiajun He, 2016

机译：通过晶体设计从聚集诱导的发射中获得纯有机发光体非常明亮的机械发光
7. Using tetraphenylethene and carbazole to create efficient luminophores with aggregation-induced emission, high thermal stability, and good hole-transporting property [O] . Zujin Zhao, Carrie Y. K. Chan, Shuming Chen, 2012

机译：使用四苯乙烯和咔唑来创造具有聚集诱导的发射，高热稳定性和良好的空穴传输性能的有效发光体

Lipofection with estrone-based luminophores featuring aggregation-induced emission properties

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