• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>RSC Advances >Pressure-assisted solvent- and catalyst-free production of well-defined poly(1-vinyl-2-pyrrolidone) for biomedical applications
【24h】

Pressure-assisted solvent- and catalyst-free production of well-defined poly(1-vinyl-2-pyrrolidone) for biomedical applications

机译：用于生物医学应用的压力辅助溶剂和无常用的聚（1-乙烯基-2-吡咯烷酮）的生产

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In this work, we developed a fast, highly efficient, and environmentally friendly catalytic system for classical free-radical polymerization (FRP) utilizing a high-pressure (HP) approach. The application of HP for thermally-induced, bulk FRP of 1-vinyl-2-pyrrolidone (VP) allowed to eliminate the current limitation of ambient-pressure polymerization of 'less-activated' monomer (LAM), characterized by the lack of temporal control yielding polymers of unacceptably large disperisites and poor result reproducibility. By a simple manipulation of thermodynamic conditions (p= 125-500 MPa,T= 323-333 K) and reaction composition (two-component system: monomer and low content of thermoinitiator) well-defined poly(1-vinyl-2-pyrrolidone)s (PVP) in a wide range of molecular weights and low/moderate dispersities (M-n= 16.2-280.5 kg mol(-1),D= 1.27-1.45) have been produced. We have found that HP can act as an 'external' controlling factor that warrants the first-order polymerization kinetics for classical FRP, something that was possible so far only for reversible deactivation radical polymerization (RDRP) systems. Importantly, our synthetic strategy adopted for VP FRP enabled us to obtain polymers of very highM(n)in a very short time-frame (0.5 h). It has also been confirmed that VP bulk polymerization yields polymers with significantly lower glass transition temperatures (T-g) and different solubility properties in comparison to macromolecules obtained during the solvent-assisted reaction.
机译：在这项工作中，我们开发了一种用于经典自由基聚合（FRP）的快速，高效，环保的催化系统，利用高压（HP）方法。 HP用于热诱导的1-乙烯基-2-吡咯烷酮（VP）的散装FRP的应用，以消除“缺失激活”单体（LAM）的环境 - 压力聚合的电流限制，其特征在于缺乏时间控制屈服于大致密性的聚合物，结果再现性差。通过简单地操纵热力学条件（P = 125-500MPa，T = 323-333 k）和反应组合物（双组分系统：单体和热引发剂的单体和低含量）明确定义的聚（1-乙烯基-2-吡咯烷酮已经制备了宽范围的分子量和低/中等分散体（Mn = 16.2-280.5kg mol（-1），d = 1.27-1.45）中的s（pvp）。我们已经发现，惠普可以充当“外部”控制因素，可根据可逆停用自由基聚合（RDRP）系统，保证古典FRP的一阶聚合动力学。重要的是，我们对VP FRP采用的合成策略使我们能够在非常短的时间框架（0.5小时）中获得非常高（n）的聚合物。还证实，与在溶剂辅助反应期间获得的大分子相比，VP散装聚合产生具有显着降低的玻璃化转变温度（T-G）和不同溶解性特性的聚合物。

著录项

  • 来源
    《RSC Advances》 |2020年第36期|共9页
  • 作者

    Maksym Paulina; Tarnacka Magdalena; Heczko Dawid; Knapik-Kowalczuk Justyna; Mielanczyk Anna; Bernat Roksana; Garbacz Grzegorz; Kaminski Kamil; Paluch Marian;

  • 作者单位

    Univ Silesia Inst Phys Ul 75 Pulku Piechoty 1 PL-41500 Chorzow Poland;

    Univ Silesia Inst Phys Ul 75 Pulku Piechoty 1 PL-41500 Chorzow Poland;

    Med Univ Silesia Sch Pharm Dept Pharmacognosy &

    Phytochem Div Lab Med Sosnowiec Jagiellonska 4 PL-41200 Sosnowiec Poland;

    Univ Silesia Inst Phys Ul 75 Pulku Piechoty 1 PL-41500 Chorzow Poland;

    Silesian Tech Univ Fac Chem Dept Phys Chem &

    Technol Polymers Ul M Strzody 9 PL-44100 Gliwice Poland;

    Univ Silesia Silesian Ctr Educ &

    Interdisciplinary Res Ul 75 Pulku Piechoty 1A PL-41500 Chorzow Poland;

    Physiolution GmbH Walther Rathenau Str 49a D-17489 Greifswald Germany;

    Univ Silesia Inst Phys Ul 75 Pulku Piechoty 1 PL-41500 Chorzow Poland;

    Univ Silesia Inst Phys Ul 75 Pulku Piechoty 1 PL-41500 Chorzow Poland;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 化学;
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号