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Application status and technical analysis of chitosan-based medical dressings: a review

机译：基于壳聚糖的医疗敷料的应用现状及技术分析：综述

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摘要

Chitosan has wide applications in the field of medical dressings due to its good biomedical properties. This review provides the application status and technical analysis of chitosan medical dressings. First, we introduce the source and chemical structure of chitosan. Then, we investigate the mechanism of chitosan showing different medical properties. We also show the application of supramolecular chitosan-based hydrogels in the dressing field and the formulation optimization and the preparation technology of chitosan dressings for fabricating chitosan-based dressings with various morphologies and medical functions. After that, we introduce the research process of the modification method of chitosan dressings including single modification, blending modification, crosslinking modification,etc.Finally, based on the study of the medical effects of chitosan dressings, we analyze the existing problems in the preparation process and propose corresponding solutions from the aspects of the morphology, clinical feedback effect, and future development trends. This paper can provide a reference for further studies of skin tissue engineering and the development of new chitosan medical dressings.
机译：壳聚糖在医用敷料领域由于其良好的生物医学性能广泛的应用。本文综述了应用现状和壳聚糖医用敷料的技术分析。首先，我们介绍了源和壳聚糖的化学结构。然后，我们研究了壳聚糖表现出不同的医疗性质的机构。我们还表明超分子壳聚糖类水凝胶在敷料领域的应用和配方的优化和各种形态和医疗功能制造壳聚糖类敷料包扎壳聚糖的制备工艺。在那之后，我们引入壳聚糖敷料包括单修改，共混改性，交联改性，etc.Finally，基于壳聚糖敷料的医疗效果研究的基础上，我们分析在制备过程中存在的问题的修改方法的研究过程并提出相应的从形态，临床反馈效应，以及未来发展趋势等方面的解决方案。本文可以为皮肤组织工程的进一步研究和新壳聚糖医用敷料的发展提供参考。

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  • 来源
    《RSC Advances》 |2020年第56期|共15页
  • 作者

    Zhang Shanguo; Li Jianyong; Li Jianfeng; Du Na; Li Donghai; Li Fangyi; Man Jia;

  • 作者单位

    Shandong Univ Minist Educ Sch Mech Engn Key Lab High Efficiency &

    Clean Mech Manufacture Jinan 250061 Peoples R China;

    Shandong Univ Minist Educ Sch Mech Engn Key Lab High Efficiency &

    Clean Mech Manufacture Jinan 250061 Peoples R China;

    Shandong Univ Minist Educ Sch Mech Engn Key Lab High Efficiency &

    Clean Mech Manufacture Jinan 250061 Peoples R China;

    Shandong Univ Dept Geriatr Affiliated Hosp 2 Jinan 250033 Peoples R China;

    Shandong Univ Adv Med Res Inst Jinan 250012 Peoples R China;

    Shandong Univ Minist Educ Sch Mech Engn Key Lab High Efficiency &

    Clean Mech Manufacture Jinan 250061 Peoples R China;

    Shandong Univ Minist Educ Sch Mech Engn Key Lab High Efficiency &

    Clean Mech Manufacture Jinan 250061 Peoples R China;

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  • 正文语种 eng
  • 中图分类 化学;
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