Nanoscopic insights into the surface conformation of neurotoxic amyloid beta oligomers

Banchelli Martina; Cascella Roberta; DAndrea Cristiano; Cabaj Leszek; Osticioli Iacopo; Ciofini Daniele; Li Mai Suan; Skupien Krzysztof; de Angelis Marella; Siano Salvatore; Cecchi Cristina; Pini Roberto; La Penna Giovanni; Chiti Fabrizio; Matteini Paolo

首页> 外文期刊>RSC Advances >Nanoscopic insights into the surface conformation of neurotoxic amyloid beta oligomers

【24h】

Nanoscopic insights into the surface conformation of neurotoxic amyloid beta oligomers

机译：纳米镜洞察神经毒性淀粉样蛋白β低聚物的表面构象

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Raman spectroscopy assisted by localized plasmon resonances generating effective hot spots at the gaps between intertwined silver nanowires is herein adopted to unravel characteristic molecular motifs on the surface of A beta(42)misfolded oligomers that are critical in driving intermolecular interactions in neurodegeneration.

机译：由局部化的等离子体谐振辅助的拉曼光谱法在本文中采用在交织银纳米线之间的间隙处产生有效的热点，在β（42）的β（42）的β（42）的表面上的解糊性的寡聚体中的衰减特征分子基质在促进神经变异间的分子间相互作用中是至关重要的。

著录项

来源
《RSC Advances》 |2020年第37期|共7页
作者
Banchelli Martina; Cascella Roberta; DAndrea Cristiano; Cabaj Leszek; Osticioli Iacopo; Ciofini Daniele; Li Mai Suan; Skupien Krzysztof; de Angelis Marella; Siano Salvatore; Cecchi Cristina; Pini Roberto; La Penna Giovanni; Chiti Fabrizio; Matteini Paolo;
展开▼
作者单位

CNR Inst Appl Phys Nello Carrara Via Madonna Piano 10 I-50019 Sesta Fiorentino Italy;

Univ Florence Dept Expt &

Clin Biomed Sci Viale Morgagni 50 I-50134 Florence Italy;

CNR Inst Appl Phys Nello Carrara Via Madonna Piano 10 I-50019 Sesta Fiorentino Italy;

3D Nano PL-30702 Krakow Poland;

CNR Inst Appl Phys Nello Carrara Via Madonna Piano 10 I-50019 Sesta Fiorentino Italy;

CNR Inst Appl Phys Nello Carrara Via Madonna Piano 10 I-50019 Sesta Fiorentino Italy;

Polish Acad Sci Inst Phys Al Lotnikow 32-46 PL-02668 Warsaw Poland;

3D Nano PL-30702 Krakow Poland;

CNR Inst Appl Phys Nello Carrara Via Madonna Piano 10 I-50019 Sesta Fiorentino Italy;

CNR Inst Appl Phys Nello Carrara Via Madonna Piano 10 I-50019 Sesta Fiorentino Italy;

Univ Florence Dept Expt &

Clin Biomed Sci Viale Morgagni 50 I-50134 Florence Italy;

CNR Inst Appl Phys Nello Carrara Via Madonna Piano 10 I-50019 Sesta Fiorentino Italy;

CNR Inst Chem Organometall Cpds Via Madonna Piano 10 I-50019 Sesto Fiorentino Italy;

Univ Florence Dept Expt &

Clin Biomed Sci Viale Morgagni 50 I-50134 Florence Italy;

CNR Inst Appl Phys Nello Carrara Via Madonna Piano 10 I-50019 Sesta Fiorentino Italy;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类化学;
关键词

相似文献

外文文献
中文文献
专利

1. Nanoscopic insights into the surface conformation of neurotoxic amyloid beta oligomers [J] . Banchelli Martina, Cascella Roberta, DAndrea Cristiano, RSC Advances . 2020,第37期

机译：纳米镜洞察神经毒性淀粉样蛋白β低聚物的表面构象
2. The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation? [J] . Kerensa Broersen, Frederic Rousseau, Joost Schymkowitz Alzheimer s Research & Therapy . 2010,第4期

机译：淀粉样蛋白β肽与阿尔茨海默氏病相关的神经毒性的元凶：寡聚物的大小或构象？
3. An N-terminal antibody promotes the transformation of amyloid fibrils into oligomers and enhances the neurotoxicity of amyloid-beta: the dust-raising effect [J] . Yu-Hui Liu, Xian-Le Bu, Chun-Rong Liang, Journal of neuroinflammation . 2015,第3期

机译：N末端抗体可促进淀粉样蛋白原纤维转化为低聚物，并增强淀粉样蛋白β的神经毒性：扬尘效果
4. STRUCTURAL INSIGHTS INTO POTENTIALLY TOXIC CONFORMATIONS OF β-AMYLOID (1-42) OLIGOMERS [C] . Rene Zangl, Janosch Martin, Tobias Lieblein, International Mass Spectrometry Conference . 2018

机译：结构洞察β-淀粉样蛋白（1-42）低聚物的潜在毒性构象
5. Role of amyloid precursor protein and amyloid-beta in Alzheimer's disease: Modulation of APP processing detection of Abeta oligomers, and their role in the pathogenesis and treatment of AD. [D] . Kim, Minkyu Leo. 2009

机译：淀粉样前体蛋白和淀粉样β在阿尔茨海默氏病中的作用：APP处理Abeta寡聚体检测的调节及其在AD的发病机理和治疗中的作用。
6. The culprit behind amyloid beta peptide related neurotoxicity in Alzheimers disease: oligomer size or conformation? [O] . Kerensa Broersen, Frederic Rousseau, Joost Schymkowitz 2010

机译：淀粉样蛋白β肽与阿尔茨海默氏病相关的神经毒性的元凶：寡聚物的大小或构象？
7. The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation? [O] . Broersen, Kerensa, Rousseau, Frederic, Schymkowitz, Joost 2010

机译：淀粉样蛋白β肽与阿尔茨海默氏病相关的神经毒性的元凶：寡聚物的大小或构象？

Nanoscopic insights into the surface conformation of neurotoxic amyloid beta oligomers

摘要

著录项

相似文献

相关主题

期刊订阅