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Hosta plantaginea (Lam.) Aschers (Yuzan): an overview on its botany, traditional use, phytochemistry, quality control and pharmacology

机译:Hosta plantaginea(林。)aschers(yuzan):概述其植物学,传统使用,植物化学,质量控制和药理学

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Hosta plantaginea (Lam.) Aschers, as a traditional folk medicine, has been widely used both as a single herb and in prescriptions in Asia mainly due to its anti-inflammatory and analgesic effects. A total of 101 compounds including steroids, flavonoids, alkaloids and others have been isolated from H. plantaginea. Modern pharmacology has revealed that H. plantaginea possesses various therapeutic effects such as anti-inflammatory, analgesic and antibacterial effects both in vitro and in vivo. Although a number of reports on the chemical constituents and pharmacological activities of this plant are available, there is limited research on the bioactive constituents and the mechanism of the biological activities of H. plantaginea. Thus, it is essential to strengthen the research on bioactive constituents and their mechanisms as well as their structure-function relationships in H. plantaginea. Up to now, only three compounds have been established for the quality control of H. plantaginea. However, a comprehensive review on the botany, traditional use, phytochemistry, quality control and pharmacology information about this plant has not been reported so far; thus, a systematic and comprehensive review is very necessary. Therefore, this paper provided a comprehensive overview on the botany, traditional use, phytochemistry, quality control and pharmacology of H. plantaginea and also provided evidence for its further research and clinical applications.
机译:作为一种传统的民间医学,Hosta Plantaginea(Lam。)aschers已被广泛使用,既广泛用作唯一的草药和亚洲处方,主要是由于其抗炎和镇痛作用。总共101种化合物,包括类固醇,黄酮类化合物,生物碱等已从H.Purlaginea中分离出来。现代药理学揭示了H.Plantaginea具有各种治疗效果,例如体外和体内抗炎,镇痛和抗菌作用。尽管有许多关于该植物的化学成分和药理活性的报告,但对生物活性成分的研究有限研究了H.Plantaginea的生物活性的机制。因此,必须加强对生物活性成分及其机制的研究以及H.Plantaginea的结构功能关系。到目前为止,只有三种化合物已经为H.Plantaginea的质量控制建立。然而,到目前为止还没有向植物学,传统使用,植物化学,质量控制和药理学信息进行全面审查;因此,系统和全面的审查是非常必要的。因此,本文提供了对植物学,传统使用,植物化学,H.Plantaginea的质量控制和药理学的全面概述,并为其进一步的研究和临床应用提供了证据。

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    《RSC Advances》 |2019年第60期|共9页
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