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Repair of dentine-related lesions without a drill or injection

机译:没有钻头或注射的牙本质相关病变的修复

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摘要

For covering the shortages of traditional treatments, a novel and non-invasive system was developed with the simple adaption of nature's own repair process, while an extrinsic electric field was introduced to improve its remineralization kinetics. In an in vivo study, acid-etched rabbit dentine was used to evaluate the remineralization efficacy and safety of the system. The exposed dentine tubules were fully occluded after 5 hours/1.0 mA and 8 hours/0.5 mA of remineralization. After 5 hours of remineralization (1.0 mA), the micro-hardness of the demineralized dentine was fully recovered, equal to native rabbit dentine. Haematoxylin-eosin staining demonstrated no obvious inflammatory reaction. This study provides a feasible solution to realize rapid repair of dentine.
机译:为了涵盖传统治疗的短缺,具有简单的自然自身修复过程的简单适应,引入了一种新颖和非侵入性系统,而引入外部电场以改善其再矿化动力学。 在体内研究中,使用酸蚀刻的兔牙本丁来评估系统的再矿化功效和安全性。 暴露的牙本质小管在5小时/ 1.0mA和8小时/ 0.5mA的再矿化后完全堵塞。 在剩余5小时后(1.0mA),脱矿质牙本质的微硬度完全回收,等于天然兔牙本质。 血红素 - 曙红染色证明没有明显的炎症反应。 本研究提供了一种可行的解决方案,以实现牙本质的快速修复。

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  • 来源
    《RSC Advances》 |2019年第26期|共9页
  • 作者单位

    Univ Hong Kong Prince Philip Dent Hosp Fac Dent 34 Hosp Rd Hong Kong Peoples R China;

    Univ Hong Kong Prince Philip Dent Hosp Fac Dent 34 Hosp Rd Hong Kong Peoples R China;

    Univ Hong Kong Prince Philip Dent Hosp Fac Dent 34 Hosp Rd Hong Kong Peoples R China;

    Anhui Med Univ Coll &

    Hosp Stomatol Dept Prosthodont 69 Meishan Rd Hefei Anhui Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 化学;
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