• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>RSC Advances >Contact lenses for continuous corneal temperature monitoring
【24h】

Contact lenses for continuous corneal temperature monitoring

机译：用于连续角膜温度监测的隐形眼镜

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Temperature variation is a ubiquitous medical sign to monitor ocular conditions including dry eye disease (DED), glaucoma, carotid artery stenosis, diabetic retinopathy, and vascular neuritis. The ability to measure OST in real time is desirable in point-of-care diagnostics. Here, we developed minimally invasive contact lens temperature sensors for continuous monitoring of the corneal temperature. The contact lens sensor consisted of a laser patterned commercial contact lens embedding temperature-sensitive Cholesteric Liquid Crystals (CLCs), which exhibited a fully reversible temperature-dependent color change in the visible spectrum. The contact lens allowed the corneal temperature to be mapped in four key areas, at distances of 0.0, 1.0, 3.0, and 5.0mm from the pupil's edge. Liquid crystals exhibited a wavelength shift from 738 +/- 4 nm to 474 +/- 4 nm upon increasing the temperature from 29.0 degrees C to 40.0 degrees C, with a time responsivity of 490 ms and a negligible hysteresis. Readouts were performed using a smartphone, which output RGB triplets associated to temperature values. Contact lens sensors based on CLCs were fitted and tested on an ex vivo porcine eye and readouts were compared with infrared thermal measurements, resulting in an average difference of 0.3 degrees C.
机译：温度变化是一种普遍存在的医学标志，用于监测眼科病症，包括干眼症（DED），青光眼，颈动脉狭窄，糖尿病视网膜病变和血管神经炎。实时测量OST的能力是可取的，以便在护理点诊断中。在这里，我们开发了微创隐形眼镜温度传感器，用于连续监测角膜温度。隐形眼镜传感器由激光图案化的商业隐形眼镜嵌入温度敏感的胆甾型液晶（CLC）组成，其在可见光谱中表现出完全可逆的温度依赖性颜色变化。隐形眼镜允许距离四个关键区域的角膜温度，距离瞳孔边缘0.0,1.0,3.0，5.0mm的距离。液晶在将温度从29.0℃至40.0摄氏度的温度增加到738 +/- 4nm至474 +/- 4nm的波长偏移，时间响应率为490ms和可忽略的滞后。使用智能手机执行读数，该智能手机输出与温度值相关的RGB三元组。基于CLCS的隐形眼镜传感器拟合并在前体内猪眼中进行测试，并将读出与红外热测量进行比较，导致平均差为0.3℃。

著录项

  • 来源
    《RSC Advances》 |2019年第20期|共10页
  • 作者

    Moreddu Rosalia; Elsherif Mohamed; Butt Haider; Vigolo Daniele; Yetisen Ali K.;

  • 作者单位

    Imperial Coll London Dept Chem Engn London SW7 2AZ England;

    Univ Birmingham Sch Chem Engn Birmingham B15 2TT W Midlands England;

    Khalifa Univ Dept Mech Engn Abu Dhabi 127788 U Arab Emirates;

    Univ Birmingham Sch Chem Engn Birmingham B15 2TT W Midlands England;

    Imperial Coll London Dept Chem Engn London SW7 2AZ England;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 化学;
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号