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Laser-induced selective wax reflow for paper-based microfluidics

机译：激光诱导的纸张微流体选择性蜡回流

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摘要

This study proposes a novel method for the fabrication of paper-based microfluidic devices using laser-induced selective thermal reflow for wax penetration. A layer of wax was evenly deposited on the front side of a filter paper; then a low-cost diode laser was used to scan the designed area from the back side of the filter paper. At the laser irradiated spot, the wax was heated, melted down and penetrated through the whole thickness of the filter paper, and formed hydrophobic barriers on the hydrophilic cellulose fibers. The patterned hydrophobic wax barriers on the filter paper defined the flow path of the fluid for the paper-based microfluidic device. Compared with conventional two-step (deposit and reflow) approaches for paper-based microfluidics using wax barriers, e.g. wax printing, stamping or photolithography, the proposed fabrication protocol achieved wax patterning and reflow simultaneously, conducted during the laser scan process, and without the requirement for any sophisticated instruments or a cleanroom environment. A series of tests were also conducted for the characterization of the proposed paper-based microfluidic device fabrication technique. The fabrication technique used in this approach could have broad application potential in point-of-care diagnosis and testing, especially for applications in the developing world.
机译：该研究提出了一种使用激光诱导的选择性热回流制造纸基微流体装置的新方法，以进行蜡渗透。一层蜡均匀地沉积在滤纸的前侧;然后使用低成本二极管激光器从滤纸的后侧扫描设计的面积。在激光照射点，将蜡加热，熔化并穿过滤纸的整个厚度，并在亲水纤维素纤维上形成疏水屏障。滤纸上的图案化的疏水蜡屏障限定了用于纸基微流体装置的流体的流动路径。与常规两步（沉积和回流）相比，使用蜡屏障的纸质微流体方法，例如，使用蜡屏障。蜡印刷，冲压或光刻，所提出的制造方案同时实现了蜡图案和回流，在激光扫描过程中进行，并且在没有任何复杂的仪器或洁净室环境的要求下进行。还进行了一系列测试，用于表征所提出的基于纸的微流体装置制造技术。这种方法中使用的制造技术可以在护理点诊断和测试中具有广泛的应用潜力，特别是对于发展中国家的应用。

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  • 来源
    《RSC Advances》 |2019年第20期|共5页
  • 作者

    Zhang Yajun; Liu Jingji; Wang Hongliang; Fan Yiqiang;

  • 作者单位

    Beijing Univ Chem Technol Sch Mech &

    Elect Engn Beijing 100029 Peoples R China;

    Beijing Univ Chem Technol Sch Mech &

    Elect Engn Beijing 100029 Peoples R China;

    Beijing Univ Chem Technol Sch Mech &

    Elect Engn Beijing 100029 Peoples R China;

    Beijing Univ Chem Technol Sch Mech &

    Elect Engn Beijing 100029 Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 化学;
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