• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>RSC Advances >Cell viability and hydration assay based on metamaterial-enhanced terahertz spectroscopy
【24h】

Cell viability and hydration assay based on metamaterial-enhanced terahertz spectroscopy

机译：基于超材料增强的太赫兹光谱的细胞活力和水化测定

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

As a fast-growing technology, terahertz time-domain spectroscopy (THz-TDS) is becoming increasingly pervasive in biological applications, targeting a range of biomaterials from biomolecules to tissues. However, THz-TDS studies at the cellular level are quite limited. Thus, a study to analyze the living state and hydration state of a tumor cell in a label-free manner is carried out and reported here. Combined with a specially designed THz metamaterial, a tumor cell monolayer was detected continuously over a period of time. In addition, in order to explore the possible impact of the metamaterial on tumor cells, the secretion of IL-6, IL-8, GM-CSF and GRO alpha of cell supernatants was detected. The results demonstrated that the technology could characterize the living state by monitoring the extracellular water and investigate the hydration state inside a tumor cell in real time, showing great application potential for the label-free detection of normal cells and tumor cells of diverse malignant degree.
机译：作为一个快速发展的技术，太赫兹时域分光法（太赫兹TDS）正在成为生物应用越来越普遍，靶向范围的生物材料从生物分子组织。然而，在细胞水平太赫兹时域的研究十分有限。因此，研究，分析肿瘤细胞的生存状态和水合状态在无标记的方式进行，在这里报道。用专门设计的太赫兹超材料，单层在一段时间内连续检测到的肿瘤细胞结合。此外，为了探讨对肿瘤细胞的特异材料可能造成的影响，IL-6的分泌，IL-8，检测GM-CSF和细胞上清液的GRO阿尔法。结果表明，该技术可通过监测细胞外水表征的生存状态，探讨实时肿瘤细胞内的水合状态，表现出对正常细胞和多样化的恶性程度的肿瘤细胞的无标记检测很大的应用潜力。

著录项

  • 来源
    《RSC Advances》 |2017年第85期|共7页
  • 作者

    Liu Yu; Tang Mingjie; Xia Liangping; Yu Wenjing; Peng Jia; Zhang Yang; de la Chapelle Marc Lamy; Yang Ke; Cui Hong-Liang; Fu Weiling;

  • 作者单位

    Third Mil Med Univ Southwest Hosp Dept Lab Med Chongqing 400038 Peoples R China;

    Chinese Acad Sci Chongqing Inst Green &

    Intelligent Technol Chongqing Key Lab Multiscale Mfg Technol Chongqing 400714 Peoples R China;

    Chinese Acad Sci Chongqing Inst Green &

    Intelligent Technol Chongqing Key Lab Multiscale Mfg Technol Chongqing 400714 Peoples R China;

    Third Mil Med Univ Southwest Hosp Dept Lab Med Chongqing 400038 Peoples R China;

    Third Mil Med Univ Southwest Hosp Dept Lab Med Chongqing 400038 Peoples R China;

    Third Mil Med Univ Southwest Hosp Dept Lab Med Chongqing 400038 Peoples R China;

    Univ Paris 13 CNRS Lab CSPBAT UMR 7244 Sorbonne Paris Cite 74 Rue Marcel Cachin F-93017 Bobigny France;

    Third Mil Med Univ Southwest Hosp Dept Lab Med Chongqing 400038 Peoples R China;

    Chinese Acad Sci Chongqing Inst Green &

    Intelligent Technol Chongqing Key Lab Multiscale Mfg Technol Chongqing 400714 Peoples R China;

    Third Mil Med Univ Southwest Hosp Dept Lab Med Chongqing 400038 Peoples R China;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 化学;
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号