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Uniform focusing with an extended depth range and increased working distance for optical coherence tomography by an ultrathin monolith fiber probe

机译:通过超薄的整体纤维探针均匀聚焦,具有扩展深度范围和光学相干断层扫描的工作距离增加

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It is difficult to maintain high transverse resolution over an increased depth range using miniature probes for optical coherence tomography (OCT) due to the rapid divergence of light and the space limitation. To solve this problem, we introduce a fiber-based filter in the proposed probe to manipulate its output beam. Significant mode interference (MI) is exploited to enhance the depth of focus (DOF), and the mode phase difference is tuned to achieve a uniform axial intensity within the DOE The magnified MI field instead of the diffracted one is adopted as the final pupil filter in the probe to increase its working distance (WD). The probe is fabricated with a diameter of 125 mu m and a total length of 2.6 mm for its distal fiber optics. Compared to the conventional probe with similar minimal lateral resolution of better than 4.4 mu m, the proposed probe achieves two times that of the DOF gain and 1.7 times that of the WD. Improvements in performance of the probe are demonstrated by OCT imaging using a fresh lemon and human skin. With merits of enhanced imaging quality and easy fabrication, the proposed probe poses great potential for important applications, especially for endoscopic imaging of human internal organs in vivo. (C) 2020 Optical Society of America
机译:难以使用微型探针光学相干断层扫描,以保持在一个增大的深度范围内的高横向分辨率(OCT)由于光的发散迅速和空间的限制。为了解决这个问题,我们在所提出的探针中引入基于光纤的滤波器以操纵其输出波束。利用显着的模式干扰(MI)以增强聚焦深度(DOF),并且调谐模式差异以在最终瞳孔过滤器中采用衍射的MI字段内实现均匀的轴向强度。在探针中增加其工作距离(WD)。探针制造,直径为125μm,其远端光纤的总长度为2.6mm。与具有类似的横向分辨率的常规探针比4.4μm更大的探针相比,所提出的探针达到DOF增益的两倍和WD的1.7倍。 OCT成像使用新鲜的柠檬和人体皮肤来证明探针性能的改进。具有增强的成像质量和易于制造的优点,所提出的探针对重要应用构成很大的潜力,特别是对于体内人类内脏的内窥镜成像。 (c)2020美国光学学会

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