Optoretinogram: optical measurement of human cone and rod photoreceptor responses to light

Azimipour Mehdi; Valente Denise; Vienola Kari V.; Werner John S.; Zawadzki Robert J.; Jonnal Ravi S.

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Optoretinogram: optical measurement of human cone and rod photoreceptor responses to light

机译：OptoretinoGro：人锥和杆光感受器的光学测量对光的反应

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Noninvasive, objective measurement of rod function is as significant as that of cone function, and for retinal diseases such as retinitis pigmentosa and age-related macular degeneration, rod function may be a more sensitive biomarker of disease progression and efficacy of treatment than cone function. Functional imaging of single human rod photoreceptors, however, has proven difficult because their small size and rapid functional response pose challenges for the resolution and speed of the imaging system. Here, we describe light-evoked, functional responses of human rods and cones, measured noninvasively using a synchronized. adaptive optics optical coherence tomography (OCT) and. scann ing light ophthalmoscopy (SW) system. The higher lateral resolution of the SW images made it possible to confirm the identity of rods in the corresponding OCT volumes. (C) 2020 Optical Society of America

机译：非侵入性的，客观测量的杆函数与锥体功能一样重要，并且对于视网膜疾病，如视网膜炎和年龄相关的黄斑变性，杆功能可能是疾病进展的更敏感的生物标志物，而不是治疗的疗效而不是锥体功能。然而，单个人杆光感受器的功能成像已经证明是困难的，因为它们的小尺寸和快速的功能响应对成像系统的分辨率和速度构成挑战。在这里，我们描述了人杆和锥体的光诱发功能响应，使用同步测量。自适应光学光学相干断层扫描（OCT）和。扫描光眼镜镜（SW）系统。 SW图像的较高横向分辨率使得可以在相应的OCT体积中确认杆的身份。（c）2020美国光学学会

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来源
《Optics Letters》 |2020年第17期|共4页
作者
Azimipour Mehdi; Valente Denise; Vienola Kari V.; Werner John S.; Zawadzki Robert J.; Jonnal Ravi S.;
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作者单位

UC Davis Eye Ctr Dept Ophthalmol &

Vis Sci Vis Sci &

Adv Retinal Imaging Lab VSRI Sacramento CA 95817 USA;

UC Davis Eye Ctr Dept Ophthalmol &

Vis Sci Vis Sci &

Adv Retinal Imaging Lab VSRI Sacramento CA 95817 USA;

UC Davis Eye Ctr Dept Ophthalmol &

Vis Sci Vis Sci &

Adv Retinal Imaging Lab VSRI Sacramento CA 95817 USA;

UC Davis Eye Ctr Dept Ophthalmol &

Vis Sci Vis Sci &

Adv Retinal Imaging Lab VSRI Sacramento CA 95817 USA;

UC Davis Eye Ctr Dept Ophthalmol &

Vis Sci Vis Sci &

Adv Retinal Imaging Lab VSRI Sacramento CA 95817 USA;

UC Davis Eye Ctr Dept Ophthalmol &

Vis Sci Vis Sci &

Adv Retinal Imaging Lab VSRI Sacramento CA 95817 USA;

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原文格式 PDF
正文语种 eng
中图分类计量学;光学;
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1. Optoretinogram: optical measurement of human cone and rod photoreceptor responses to light [J] . Azimipour Mehdi, Valente Denise, Vienola Kari V., Optics Letters . 2020,第17期

机译：OptoretinoGro：人锥和杆光感受器的光学测量对光的反应
2. Melanopsin and Rod-cone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans [J] . GooleyJ.J., MienI.H., St.HilaireM.A., The Journal of Neuroscience: The Official Journal of the Society for Neuroscience . 2012,第41期

机译：黑色素和棒锥感光细胞在人类暴露于连续光过程中在调节瞳孔光反应中发挥不同的作用
3. Speed, sensitivity, and stability of the light response in rod and cone photoreceptors: Facts and models [J] . KorenbrotJ.I. Progress in retinal and eye research . 2012,第5期

机译：杆和锥型感光体中光响应的速度，灵敏度和稳定性：事实和模型
4. Classifying cone photoreceptors in the living human eye using their unique phase response to light [C] . Furu Zhang, Kazuhiro Kurokawa, Ayoub Lassoued, Ophthalmic Technologies XXIX . 2019

机译：使用人眼对光的独特相位响应来对视锥细胞进行分类
5. Turning off the light response in rod and cone photoreceptors. [D] . Kennedy, Matthew James. 2003

机译：关闭棒形和锥形感光器的光响应。
6. Melanopsin and Rod–Cone Photoreceptors Play Different Roles in Mediating Pupillary Light Responses during Exposure to Continuous Light in Humans [O] . Joshua J. Gooley, Ivan Ho Mien, Melissa A. St. Hilaire, 2012

机译：黑素和杆状锥感光细胞在人类连续光照射过程中在调节瞳孔光反应中起不同作用
7. Optoretinography: optical measurements of human cone and rod photoreceptor responses to light [O] . Mehdi Azimipour, Denise Valente, Kari V. Vienola, 2019

机译：Optoretinography：人体锥形和杆光感受器的光学测量对光反应

Optoretinogram: optical measurement of human cone and rod photoreceptor responses to light

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