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Quantification of number density of random microstructure from a photoacoustic signal by using Nakagami statistics

机译:使用Nakagami统计量通过光声信号量化随机微观结构的数量密度

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摘要

Tissue microstructure characterization is a valuable tool in diagnosis and staging of many diseases. In this study, we propose a photoacoustic Nakagami statistics method to noninvasively evaluate the number density of random microstructure. The Nakagami parameters are acquired by fitting the photoacoustic signal envelope histogram with Nakagami distribution function. Theoretical calculations and phantom experiments demonstrate that the Nakagami shape parameter is only related to the number density of random microstructure and monotonically increases with the number density. Based on this finding, we propose a photoacoustic tomography modality with the imaging contrast of the Nakagami shape parameter. Experiments show that the proposed method can provide more comprehensive and accurate description of tissue microstructure. (C) 2019 Optical Society of America
机译:组织微观结构表征是许多疾病的诊断和分期中的有价值的工具。 在这项研究中,我们提出了一种光声的Nakagami统计方法,以非侵略地评估随机微观结构的数量密度。 通过使用Nakagami分布功能拟合光声信号包络直方图来获取Nakagami参数。 理论计算和幻像实验表明,Nakagami形状参数仅与随机组织的数量密度有关,并用数量密度单调增加。 基于这一发现,我们提出了一种光声断层扫描模型,具有纳卡马伊形状参数的成像对比。 实验表明,该方法可以提供组织微观结构的更全面和准确的描述。 (c)2019年光学学会

著录项

  • 来源
    《Optics Letters》 |2019年第12期|共4页
  • 作者单位

    Nanjing Univ Collaborat Innovat Ctr Adv Microstruct Dept Phys MOE Key Lab Modern Acoust Nanjing 210093 Jiangsu Peoples R China;

    Nanjing Univ Collaborat Innovat Ctr Adv Microstruct Dept Phys MOE Key Lab Modern Acoust Nanjing 210093 Jiangsu Peoples R China;

    Nanjing Univ Collaborat Innovat Ctr Adv Microstruct Dept Phys MOE Key Lab Modern Acoust Nanjing 210093 Jiangsu Peoples R China;

    Nanjing Univ Collaborat Innovat Ctr Adv Microstruct Dept Phys MOE Key Lab Modern Acoust Nanjing 210093 Jiangsu Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 计量学;光学;
  • 关键词

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