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Cost-effective imaging of optoacoustic pressure, ultrasonic scattering, and optical diffuse reflectance with improved resolution and speed

机译:具有改进的分辨率和速度的优化压力,超声波散射和光学漫射反射的经济高效成像

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The idea of a method of cost-effective upgrades from an acoustic resolution photoacoustic microscope to a triple-modality imaging system is validated using phantoms. The newly developed experimental setup is based on a diode pumped solid state laser coupled to a fiber bundle with a spherically focused polyvinylidene fluoride detector integrated into the center of a ring shaped optical illuminator. Each laser pulse illuminating the sample performs two functions. While the photons absorbed by the sample provide a measurable optoacoustic (OA) signal, the photons absorbed by the detector provide the measurable diffuse reflectometry (DR) signal from the sample and the probing ultrasonic (US) pulse. At a 3 mm imaging depth, the axial resolution of the OA/US modalities is 38 mu m/26 mu m, while the lateral resolution of the DR/OA/US modalities is 3.5 mm/50 mu m/35 mu m. The maximum acquisition rate of the trimodal DR/OA/US A-scans is 2 kHz. (C) 2016 Optical Society of America
机译:使用幽灵验证了从声学分辨率的光声显微镜到三重模型成像系统的经济高效升级方法的思想。 新开发的实验设置基于二极管泵浦固态激光器,其耦合到纤维束,具有集成到环形光学发光器的中心的球形聚偏二氟乙烯检测器。 照明样品的每个激光脉冲执行两个功能。 当样品吸收的光子提供可测量的光声(OA)信号时,由检测器吸收的光子从样品和探测超声(US)脉冲中提供可测量的漫反射仪(DR)信号。 在3毫米的成像深度下,OA /美国方式的轴向分辨率为38μm/26μm,而DR / OA / US样式的横向分辨率为3.5mm /50μm/35μm。 Trimodal DR / OA / US A-Scans的最大采集率为2 kHz。 (c)2016年光学学会

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