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Spatially encoded polarization-dependent nonlinear optics

机译:空间编码偏振依赖性非线性光学器件

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A single fixed optic is combined with the sample translation capabilities inherent to most microscopes to achieve precise polarization-dependent second harmonic generation microscopy measurements of thin tissue sections. Although polarization measurements have enabled detailed structural analysis of collagen, challenges in integrating rotation stages or fast electro-optic/photoelastic modulation have complicated the retrofitting of existing systems for precise polarization analysis. Placing a static microretarder array in the rear conjugate plane resulted in spatially encoded polarization modulation across the field of view. A complete set of polarization rotation measurements was acquired at each pixel by sample translation, recovering local-frame tensors relating to structure within collagenous tissue. (c) 2018 Optical Society of America
机译:单个固定光学器件与大多数显微镜固有的样本转换能力相结合,以实现精确的偏振依赖性二次谐波产生显微镜测量薄组织部分。 尽管极化测量使得能够对胶原蛋白的详细结构分析,但整合旋转阶段或快速电光/光弹性调制的挑战使现有系统的改装复杂化了精确的极化分析。 将静态微串阵列放置在后缀合物平面中,导致跨视野中的空间编码的偏振调制。 通过样本转换在每个像素中在每个像素中获得一组完整的偏振旋转测量,从而恢复与胶原组织内的结构相关的局部框架张量。 (c)2018年光学学会

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