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Outcomes of pure laparoscopic Glissonian pedicle approach hepatectomy for hepatocellular carcinoma: a propensity score matching analysis

机译:纯腹腔镜的结果浸泡肝切除术治疗肝细胞癌:促进分数匹配分析

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BackgroundFew studies had been performed to concern the outcomes of pure laparoscopic Glissonian pedicle approach hepatectomy (LGAH) for hepatocellular carcinoma (HCC). The aim of this study was to compare the outcomes of LGAH versus open Glissonian pedicle approach hepatectomy (OGAH) for HCC, especially in patients with cirrhosis.MethodsHepatocellular carcinoma patients who underwent pure LGAH and OGAH between January 2015 and July 2017 in our institution were retrospectively enrolled in this study. Propensity score matching (PSM) of patients in a ratio of 1:1 was conducted to adjust the known confounders. The perioperative and oncological outcomes were compared between the two groups after PSM.ResultsSome 80 patients underwent pure LGAH and 134 had OGAH. After PSM, 67 patients in each group were well matched for analysis. Both the postoperative overall complication rates (13.4% vs. 29.9%, P=0.021) and mean comprehensive complication index (2.63 vs. 7.40, P=0.035) were significantly lower in the LGAH group than those in OGAH group. Although the operative time was longer in the LRH group (P<0.001), the length of postoperative hospital stay was shorter in the LRH group (P=0.024). Furthermore, both the 3-year overall survival rate (73.3% for LGAH vs. 77.8% for OGAH, P=0.338) and 3-year disease-free survival rate (56.4% for LGAH vs. 62.5% for OGAH, P=0.455) were not significantly different between the groups.ConclusionPure laparoscopic Glissonian approach may be a better alternative to open Glissonian approach in selected HCC patients, which provided fewer complications, shorter postoperative hospital stay and comparable oncological outcomes.
机译:背景日复历已经进行了涉及纯腹腔镜无光泽型椎弓根椎弓根术治疗肝切除术(LGAH)的肝细胞癌(HCC)的结果。本研究的目的是比较LGAH与Open Glissonian Depice肝切除术(oOgah)的HCC的结果,特别是在肝硬化的患者中。在2015年1月至2017年1月在2017年1月之间接受纯LGAH和OGAH的患者,我们的机构回顾性注册了这项研究。进行比例为1:1的患者的倾向得分(PSM)以调节已知的混血剂。在PSM.Resultssomesome 80患者接受纯LGAH和134患者后比较两组之间的围手术期和肿瘤学结果。 PSM,每组67名患者均匀匹配分析。术后整体并发症率(13.4%对29.9%,P = 0.021)和平均综合并发症指数(2.63 vs.7.40,P = 0.035)在LGAH组中显着低于oOGAH组。虽然LRH群中的手术时间较长(P <0.001),但术后医院住院的长度在LRH组中短(P = 0.024)。此外,对于3年的总生存率(LGAH的73.3%为77.3%,对于oOgah,P = 0.338)和3年的无病生存率(LGAH的56.4%,对于oOGAH,P = 0.455 )组之间没有显着差异.Conclusionpurepurepure腹腔镜无光泽尼人方法可能是在选定的HCC患者中开放无耻的方法的更好的选择,这提供了更少的并发症,术后术后较短和可比的肿瘤学结果。

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  • 来源
    《Surgical Endoscopy》 |2019年第4期|共12页
  • 作者单位

    Sichuan Univ West China Hosp Dept Liver Surg 37 Guo Xue Rd Chengdu 610041 Sichuan Peoples R;

    Sichuan Univ West China Hosp Dept Liver Surg 37 Guo Xue Rd Chengdu 610041 Sichuan Peoples R;

    Sichuan Univ West China Hosp Dept Liver Surg 37 Guo Xue Rd Chengdu 610041 Sichuan Peoples R;

    Sichuan Univ West China Hosp Dept Liver Surg 37 Guo Xue Rd Chengdu 610041 Sichuan Peoples R;

    Sichuan Univ West China Hosp Dept Pancreat Surg Chengdu Sichuan Peoples R China;

    Sichuan Univ West China Hosp Dept Liver Surg 37 Guo Xue Rd Chengdu 610041 Sichuan Peoples R;

    Sichuan Univ West China Hosp Dept Liver Surg 37 Guo Xue Rd Chengdu 610041 Sichuan Peoples R;

    Sichuan Univ West China Hosp Dept Liver Surg 37 Guo Xue Rd Chengdu 610041 Sichuan Peoples R;

    Sichuan Univ West China Hosp Dept Liver Surg 37 Guo Xue Rd Chengdu 610041 Sichuan Peoples R;

    Sichuan Univ West China Hosp Dept Liver Surg 37 Guo Xue Rd Chengdu 610041 Sichuan Peoples R;

    Sichuan Univ West China Hosp Dept Liver Surg 37 Guo Xue Rd Chengdu 610041 Sichuan Peoples R;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 诊断学;
  • 关键词

    Laparoscopic hepatectomy; Open hepatectomy; Glissonian approach; Hepatocellular carcinoma;

    机译:腹腔镜肝切除术;开放肝切除术;无光泽的方法;肝细胞癌;

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