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Activated carbon fiber filters could reduce the risk of surgical smoke exposure during laparoscopic surgery: application of volatile organic compounds

机译:活性炭纤维过滤器可以降低腹腔镜手术期间外科烟雾暴露的风险:挥发性有机化合物的应用

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摘要

Background Generation of smoke is inevitable during surgical procedures. Some volatile organic compounds (VOCs) in surgical smoke are known to be strong carcinogens. We used a prototype of a multi-layered complex filter in an attempt to eliminate VOCs. Methods From June 2015 to July 2015, 20 patients underwent transperitoneal laparoscopic nephrectomy for renal cell carcinoma. Smoke (pre-filter) was collected 20?min after the electrocautery device was first used during the surgery, by the direct collection method, with a 5-L Tedlar? gas-sampling bag. Twenty and 120?min after the filter was applied, smoke (post-filter) was again collected using the same method. The sample was analyzed by gas chromatography and mass spectrography. The cancer risk and hazard quotient were analyzed based on US Environmental Protection Agency guidelines. Results Twenty patients with a median age of 54.5 (30–80) years were enrolled in the study. Eighteen VOCs were detected using the Japanese indoor air standards mix analysis. The total elimination rate of the VOCs was 86.49?±?2.83%. The post-filter (120?min) cancer risk (mean?±?standard deviation) reduced to a negligible level for benzene, ethylbenzene, and styrene except 1,2-dichloroethane. The post-filter (120?min) hazard quotient for each compound decreased to levels posing a negligible risk for acetone, hexane, benzene, toluene, p -xylene, o -xylene, and styrene. Conclusion Strong carcinogens, such as 1,2-dichloroethane, benzene, and ethylbenzene, were eliminated by more than 85% by using this activated carbon fiber filter and the risks from these compounds decreased to an almost negligible level. We suggest using every measure, including these filters, to protect the health of operating room personnel.
机译:在外科手术期间,背景生成烟雾是不可避免的。已知外科烟雾中的一些挥发性有机化合物(VOC)是强的致癌物质。我们使用多层复杂过滤器的原型试图消除VOC。方法从2015年6月到2015年7月,20例患者接受翻盖腹腔镜肾切除术治疗肾细胞癌。在手术期间首次使用电烙装置后收集烟雾(预过滤器)20?分钟,通过直接收集方法,用5-L刺激?气体取样袋。在施用过滤器后,二十和120?分钟,使用相同的方法再次收集烟雾(后过滤器)。通过气相色谱和质谱分析样品。根据美国环境保护机构指南分析癌症风险和危险商。结果二十例患有54.5岁(30-80)年的患者参加了该研究。使用日本室内空气标准混合分析检测十八VOC。 VOC的总消除率为86.49?±2.83%。后滤器(120?min)癌症风险(平均值?±标准偏差)减少到苯,乙苯和苯乙烯以外的忽略水平,除了1,2-二氯乙烷。每个化合物的过滤器(120?min)危险商降低到丙酮,己烷,苯,甲苯,对丙烯,o - o-any和苯乙烯的忽略风险。结论通过使用该活性炭纤维过滤器通过85%消除了1,2-二氯乙烷,苯和乙苯等强致癌物质,并且这些化合物的风险降低至几乎可忽略的水平。我们建议使用每种措施,包括这些过滤器,保护手术室人员的健康。

著录项

  • 来源
    《Surgical Endoscopy》 |2018年第10期|共9页
  • 作者单位

    Department of Urology School of Medicine Kyungpook National University;

    Department of Architectural Engineering Kyungil University;

    Department of Architectural Engineering University of Seoul;

    Department of Urology Kyungpook National University Hospital;

    Department of Urology School of Medicine Kyungpook National University;

    Department of Urology School of Medicine Kyungpook National University;

    Department of Urology School of Medicine Kyungpook National University;

    Department of Urology School of Medicine Kyungpook National University;

    Department of Urology School of Medicine Kyungpook National University;

    Department of Urology School of Medicine Kyungpook National University;

    Department of Urology School of Medicine Kyungpook National University;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 诊断学;
  • 关键词

    Surgical smoke; Laparoscopy; Cancer risk;

    机译:手术烟雾;腹腔镜检查;癌症风险;

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