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首页> 外文期刊>Surgical Endoscopy >A prospective randomized trial of EUS-guided tissue acquisition using a 25-gauge core biopsy needle with and without a stylet
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A prospective randomized trial of EUS-guided tissue acquisition using a 25-gauge core biopsy needle with and without a stylet

机译：使用25尺度核心活检针和没有探针使用25尺核心活检针的令人垂的随机试验

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Background Endoscopic ultrasound (EUS)-guided tissue acquisition has become the most effective method of obtaining specimens from a solid lesion adjacent to the gastrointestinal tract. No data exist regarding the use of a stylet in the core biopsy needle during EUS-guided tissue acquisition. The aims of this study were to evaluate the feasibility, safety, and diagnostic yield of a 25-gauge core biopsy needle without (S?) a stylet and to compare its performance with that of a 25-gauge core biopsy needle with (S+) a stylet in patients with solid lesions adjacent to the gastrointestinal tract. Methods From November 2013 to January 2016, we performed 114 EUS-guided tissue acquisitions for the diagnosis of solid lesions adjacent to the gastrointestinal tract in a randomized controlled trial. Patients were randomly assigned to the S+ group ( n ?=?57) or the S? group ( n ?=?57). EUS-guided tissue acquisition was performed using a 25-gauge core biopsy needle without an on-site cytopathologist. Results There were no significant differences in technical success (100 vs. 100%, p ?=?1.000), the mean number of needle passes (7.0?±?1.6 vs. 6.8?±?1.5, p ?=?0.556), needle malfunction (0 vs. 1.8%, p ?=?1.000), or complications (1.8 vs. 0%, p ?=?1.000) between the S+ and S? groups. Both groups exhibited comparable outcomes with respect to cytological diagnostic accuracy (93.0 vs. 91.2%, p ?=?1.000) and histological diagnostic accuracy (86.0 vs. 87.7%, p ?=?1.000) for malignancy. The procedure time was significantly shorter in the S? group than in the S+ group (32.4?±?11.7 vs. 39.7?±?8.6?min, p ?
机译：背景技术内窥镜超声（EUS） - 导向组织采集已成为从胃肠道附近的固体病变获得标本的最有效方法。在EUS引导的组织采集期间，没有关于在核心活检针中使用风格塞的数据。本研究的目的是评估25号核心活检针的可行性，安全性和诊断产量，无需（s？），并将其性能与25号核心活检针（S +）进行比较患有胃肠道邻近的固体病变患者的风笛。方法方法从2013年11月到2016年1月，我们对随机对照试验中的胃肠道邻近胃肠道的固体病变进行了114令牌的组织采集。患者被随机分配给S +组（n？= 57）或s？组（n？=？57）。使用25号核心活组织检查针对没有现场细胞病理学家进行EUS引导的组织采集。结果技术成功没有显着差异（100 vs.100％，p？=？1.000），针线的平均数量（7.0？±1.1.6与6.8？±？1.5，p？= 0.556），针故障（0 vs. 1.8％，p？=？1.000），或在S +和S之间的并发症（1.8与0％，p？=？1.000）？团体。两组对细胞学诊断准确性表现出可比的结果（93.0与91.2％，p？=β1.00）和组织学诊断准确性（86.0与87.7％，p？=？1.000）对恶性肿瘤进行恶性肿瘤。程序中的程序时间明显较短？小组比在S +组中（32.4？±11.7与39.7？±8.6？min，p？<0.001）。结论EUS引导的组织采集使用25仪表核心活检针没有风格塞特没有降低恶性肿瘤的诊断产量，并且与与探针相关的手术时间较短。

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