Effect of ulinastatin on postoperative renal function in patients undergoing robot-assisted laparoscopic partial nephrectomy: a randomized trial

Lee Bora; Lee Sook Young; Kim Na Young; Rha Koon Ho; Choi Young Deuk; Park Sujung; Kim So Yeon

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Effect of ulinastatin on postoperative renal function in patients undergoing robot-assisted laparoscopic partial nephrectomy: a randomized trial

机译：UlinAstatin对接受机器人辅助腹腔镜部分肾病术患者术后肾功能的影响：随机试验

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Robot-assisted laparoscopic partial nephrectomy (RLPN) is an emerging technique for treating small renal masses. Although RLPN has many advantages, ischemic kidney injury is inevitable during renal artery clamping. The overall incidence of acute kidney injury (AKI) after partial nephrectomy has been reported to be up to 39%. Moreover, effective pharmacological protection against AKI after partial nephrectomy has not yet been demonstrated. Ulinastatin has been shown to protect the kidney from ischemia/reperfusion injury via its anti-inflammatory and anti-oxidant activities. Therefore, this study aimed to evaluate the effect of ulinastatin on postoperative kidney function in patients undergoing RLPN.

机译：机器人辅助腹腔镜部分肾切除术（RLPN）是一种治疗小肾肿块的新兴技术。虽然RLPN具有许多优点，但在肾动脉夹紧期间缺血性肾损伤是不可避免的。据报道，部分肾切除术后急性肾损伤（AKI）的总发病率高达39％。此外，尚未证明在部分肾切除术后对AKI进行有效药理保护。已经证明乌司汀通过其抗炎和抗氧化活性保护肾脏免受缺血/再灌注损伤。因此，本研究旨在评估乌凡纳汀对患者术后肾功能的影响。

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来源
《Surgical Endoscopy》 |2017年第9期|共9页
作者
Lee Bora; Lee Sook Young; Kim Na Young; Rha Koon Ho; Choi Young Deuk; Park Sujung; Kim So Yeon;
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作者单位

Yonsei Univ Coll Med Dept Anesthesiol &

Pain Med 50-1 Yonsei Ro Seoul 03722 South Korea;

Ajou Univ Sch Med Dept Anesthesiol &

Pain Med Suwon South Korea;

Yonsei Univ Coll Med Dept Anesthesiol &

Pain Med 50-1 Yonsei Ro Seoul 03722 South Korea;

Yonsei Univ Coll Med Urol Sci Inst Dept Urol Seoul South Korea;

Yonsei Univ Coll Med Urol Sci Inst Dept Urol Seoul South Korea;

Yonsei Univ Coll Med Dept Anesthesiol &

Pain Med 50-1 Yonsei Ro Seoul 03722 South Korea;

Yonsei Univ Coll Med Dept Anesthesiol &

Pain Med 50-1 Yonsei Ro Seoul 03722 South Korea;

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正文语种 eng
中图分类诊断学;
关键词
Acute kidney injury; Nephrectomy; Reperfusion injury; Robotic surgical procedures; Ulinastatin;

机译：急性肾脏损伤;肾切除术;再灌注损伤;机器人外科手术;乌纳替肽;

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1. Effect of ulinastatin on postoperative renal function in patients undergoing robot-assisted laparoscopic partial nephrectomy: a randomized trial [J] . Lee Bora, Lee Sook Young, Kim Na Young, Surgical Endoscopy . 2017,第9期

机译：UlinAstatin对接受机器人辅助腹腔镜部分肾病术患者术后肾功能的影响：随机试验
2. Comparison of Kidney Function in the Early Postoperative Period in Transperitoneal Robot-Assisted Laparoscopic Partial Nephrectomy Between Anterior and Posterior Renal Tumors: A Propensity Score-Matched Study [J] . Takagi Toshio, Kondo Tsunenori, Yoshida Kazuhiko, Journal of endourology . 2018,第2期

机译：肾功能在术后时期术后术后腹腔镜部分肾切除术前后肾肿瘤的比较：倾向分数匹配研究
3. Effects of intraoperative PEEP on postoperative pulmonary complications in patients undergoing robot-assisted laparoscopic radical resection for bladder cancer or prostate cancer: study protocol for a randomized controlled trial [J] . Zhen-feng Zhou, Jun-biao Fang, Long Chen, Trials . 2019,第1期

机译：术中PEEP对膀胱癌或前列腺癌机器人辅助腹腔镜根治性切除术患者术后肺部并发症的影响：一项随机对照试验的研究方案
4. Multi-body statistical shape representation of anatomy for navigation in Robot-Assisted Laparoscopic Partial Nephrectomy [C] . Michael A.Kokko, John D.Seigne, Douglas W.Van Citters, Conference on Medical Imaging: Image-Guided Procedures, Robotic Interventions, and Modeling . 2021

机译：机器人辅助腹腔镜部分肾切除术中导航解剖学的多体统计形状表示
5. Trends and Significant Predictors of Post-operative Bleeding Requiring Blood Transfusion among Renal Cancer Patients Undergoing Nephrectomy [D] . Wen, Huei Hsun. 2019

机译：术后出血的趋势和重要预测因子，需要肾癌患者输血的肾病患者
6. Comparison of postoperative pain between laparoscopic and robot-assisted partial nephrectomies for renal tumors [O] . Seok-Joon Jin, Jun-Young Park, Doo-Hwan Kim, -1

机译：腹腔镜和机器人辅助部分肾切除术治疗肾肿瘤术后疼痛的比较
7. Effects of intraoperative PEEP on postoperative pulmonary complications in patients undergoing robot-assisted laparoscopic radical resection for bladder cancer or prostate cancer: study protocol for a randomized controlled trial [O] . Zhen-feng ZHOU, Jun-biao FANG, Long CHEN, 2019

机译：术中窥视对膀胱癌或前列腺癌患者进行机器人辅助腹腔镜切除术后术后肺并发症的影响：随机对照试验的研究方案

Effect of ulinastatin on postoperative renal function in patients undergoing robot-assisted laparoscopic partial nephrectomy: a randomized trial

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