...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Pediatric blood & cancer >Establishment of a formal program for retinoblastoma: Feasibility of clinical coordination across borders and impact on outcome
【24h】

Establishment of a formal program for retinoblastoma: Feasibility of clinical coordination across borders and impact on outcome

机译：建立一个正式的视网膜细胞瘤计划：跨境临床协调的可行性以及对结果的影响

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Abstract Retinoblastoma is an ocular tumor that occurs in young children, in either heritable or sporadic manner. The relative rarity of retinoblastoma, and the need for expensive equipment, anesthesia, and pediatric ophthalmologic expertise, are barriers for effective treatment in developing countries. Also, with an average age‐adjusted incidence of two to five cases per million children, patient number limits development of local expertise in countries with small populations. Lebanon is a small country with a population of approximately 4.5 million. In 2012, a comprehensive retinoblastoma program was formalized at the Children's Cancer Institute (CCI) at the American University of Beirut Medical Center, and resources were allocated for efficient interdisciplinary coordination to attract patients from neighboring countries such as Syria and Iraq, where such specialized therapy is also lacking. Through this program, care was coordinated across hospitals and borders such that patients would receive scheduled chemotherapy at their institution, and monthly retinal examinations and focal laser therapy at the CCI in Lebanon. Our results show the feasibility of successful collaboration across borders, with excellent patient and physician adherence to treatment plans. This was accompanied by an increase in patient referrals, which enables continued expertise development. However, the majority of patients presented with advanced intraocular disease, necessitating enucleation in 90% of eyes in unilateral cases, and more than 50% of eyes in bilateral cases. Future efforts need to focus on expanding the program that reaches to additional hospitals in both countries, and promoting early diagnosis, for further improvement of globe salvage rates.
机译：摘要视网膜母细胞瘤是一种在幼儿中发生的眼部肿瘤，以任何一种遗传或散发的方式。视网膜母细胞瘤的相对罕见，以及对昂贵设备，麻醉和儿科眼科专业知识的需求是在发展中国家有效治疗的障碍。此外，平均年龄调整后的2至5例每百万儿童的发生率，患者人数限制了具有小人群国家的当地专业知识的发展。黎巴嫩是一个人口约450万的小国。 2012年，在美国贝鲁特医疗中心的儿童癌症研究所（CCI）是一项综合的视网膜母细胞瘤计划，并分配资源以获得高效的跨学科协调，以吸引来自叙利亚和伊拉克等邻国的患者，其中包括这样的专业治疗也缺乏。通过这个计划，在医院和边界中协调护理，使得患者将在其机构获得预定的化疗，并在黎巴嫩的CCI每月视网膜检查和局灶性激光治疗。我们的结果表明，跨境成功合作的可行性，具有优秀的患者和医生遵守治疗计划。这伴随着患者推荐的增加，这使得持续的专业知识发展。然而，大多数患者患有先进的眼内疾病，需要在单侧案件中90％的眼睛中的肌肉，超过50％的双侧病例。未来的努力需要专注于扩大达到两国额外医院的计划，并促进早期诊断，以进一步提高全球救赎率。

著录项

  • 来源
    《Pediatric blood & cancer》 |2019年第11期|共7页
  • 作者

    Al‐Haddad Christiane; Bashour Ziad; Farah Lina; Bayram Layal; Merabe Zeina; Maluf Riad; Alameddine Ramzi; Eid Toufic; Geara Fadi; Wilson Matthew; Brennan Rachel; Jeha Sima; Ghanem Khaled; Yousef Rasha Al; Farah Roula; Noun Peter; Yassine Nabil; Inati Adlette; Muwakkit Samar; Abboud Miguel; Tarek Nidale; Hamideh Dima; Saab Raya;

  • 作者单位

    Department of OphthalmologyAmerican University of Beirut Medical CenterBeirut Lebanon;

    Department of OphthalmologyAmerican University of Beirut Medical CenterBeirut Lebanon;

    Children's Cancer Institute and Department of Pediatric and Adolescent MedicineAmerican University;

    Children's Cancer Institute and Department of Pediatric and Adolescent MedicineAmerican University;

    Children's Cancer Institute and Department of Pediatric and Adolescent MedicineAmerican University;

    Department of OphthalmologyAmerican University of Beirut Medical CenterBeirut Lebanon;

    Department of OphthalmologyAmerican University of Beirut Medical CenterBeirut Lebanon;

    Department of Radiation OncologyAmerican University of Beirut Medical CenterBeirut Lebanon;

    Department of Radiation OncologyAmerican University of Beirut Medical CenterBeirut Lebanon;

    Department of OphthalmologySt Jude Children's Research HospitalMemphis Tennessee;

    Department of OncologySt Jude Children's Research HospitalMemphis Tennessee;

    Department of OncologySt Jude Children's Research HospitalMemphis Tennessee;

    Basma Pediatric Oncology UnitDamascus Syria;

    Basma Pediatric Oncology UnitDamascus Syria;

    Division of Hematology/OncologyBeirut Lebanon;

    Department of PediatricsLebanese Hospital Geitaoui‐University Medical CenterBeirut Lebanon;

    Department of PediatricsMakassed General HospitalBeirut Lebanon;

    Department of PediatricsLebanese American University Medical Center‐Rizk HospitalBeirut Lebanon;

    Children's Cancer Institute and Department of Pediatric and Adolescent MedicineAmerican University;

    Children's Cancer Institute and Department of Pediatric and Adolescent MedicineAmerican University;

    Children's Cancer Institute and Department of Pediatric and Adolescent MedicineAmerican University;

    Children's Cancer Institute and Department of Pediatric and Adolescent MedicineAmerican University;

    Children's Cancer Institute and Department of Pediatric and Adolescent MedicineAmerican University;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 儿科学;
  • 关键词

    pediatric hematology/oncology; pediatric oncology; retinoblastoma;

    机译：小儿血液学/肿瘤学;儿科肿瘤学;视网膜母细胞瘤;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号