...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Fulminant Nocardiosis Due to a Multidrug-Resistant Isolate in a 12-Year-Old Immunocompetent Child
【24h】

Fulminant Nocardiosis Due to a Multidrug-Resistant Isolate in a 12-Year-Old Immunocompetent Child

机译：由于12岁的免疫活性子女抗性抗性抗性引起的漏洞

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Nocardiosis is a rare cause of infection that usually affects immunocompromised adult patients and might not be recognized by pediatricians. We report a fatal case of disseminated nocardiosis in a previously healthy child initially admitted for an abdominal mass with suspicion of a renal malignant tumor. The patient, originating from Mali without any medical history, displayed abdominal pain with progressive altered general status. Laboratory and imaging findings revealed lymphocytic meningitis and disseminated abscesses in the brain and the cerebellum and a large number of cystic lesions of the kidney. Despite being administered wide-spectrum antibiotics and antituberculous and antifungal therapies with an external ventricular drainage for intracranial hypertension, the patient died 6 days after his admission. Nocardia spp was cultured from a renal biopsy and the cerebrospinal fluid. Species identification and antibiotic susceptibility were obtained later, revealing a multidrug-resistant isolate of the Nocardia elegans/aobensis/africana complex. This case reveals the difficulties of diagnosing nocardiosis, in particular in children not known to be immunocompromised, because we face multiple differential diagnoses and the importance of treating nocardiosis appropriately because of intrinsic resistance issues.
机译：Nocardiosis是一种罕见的感染原因，通常会影响免疫功能性的成年患者，并且可能不会被儿科医生识别。我们在最初承认腹部肿瘤的先前健康的儿童中报告了致命的嗜遗产的丧失紊乱病例，怀疑肾脏恶性肿瘤。患者，源自马里没有任何病史，展示腹痛，逐渐改变了一般地位。实验室和成像发现揭示了淋巴细胞脑膜炎和脑中的脓肿脓肿和肾脏的大量囊性病变。尽管通过用于颅内高血压外部心室引流进行广谱抗生素和抗结核疗法，但患者入院后6天死亡。 Nocardia SPP从肾活检和脑脊液中培养。稍后获得了物种鉴定和抗生素敏感性，揭示了Nocardia elegans / aobensis / Afficana Complex的多药抗性分离物。这种情况揭示了诊断嗜癌症的困难，特别是在未知的儿童中，由于我们面临多种差异诊断和适当地治疗嗜酸性的重要性，因为由于内在的抵抗问题。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号