Reply to the comment on 'Monte Carlo calculated microdosimetric spread for cell nucleus-sized targets exposed to brachytherapy I-125 and Ir-192 sources and Co-60 cell irradiation'

Villegas F.; Ahnesjo A.

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Reply to the comment on 'Monte Carlo calculated microdosimetric spread for cell nucleus-sized targets exposed to brachytherapy I-125 and Ir-192 sources and Co-60 cell irradiation'

机译：回复对'Monte Carlo计算的微透过差异的评论，用于细胞核尺寸的靶向暴露于近距离放射治疗I-125和IR-192来源和CO-60细胞照射'

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A discrepancy between the Monte Carlo derived relative standard deviation sigma(rel)(z) (microdosimetric spread) and experimental data was reported by Villegas et al (2013 Phys. Med. Biol. 58 6149-62) suggesting wall effects as a plausible explanation. The comment by Lindborg et al (2015 Phys. Med. Biol. 60 8621-4) concludes that this is not a likely explanation. A thorough investigation of the Monte Carlo (MC) transport code used for track simulation revealed a critical bug. The corrected MC version yielded sigma(rel)(z) values that are now within experimental uncertainty. Other microdosimetric findings are hereby communicated.

机译：由Villegas等人（2013次Physmuctum.Med.Biol.58 6149-62）表示墙壁效应作为合理解释的墙壁影响。 Lindborg等人（2015年Phys。Med。Biol.60 8621-4）的结论是，这不是一个可能的解释。用于轨道仿真的蒙特卡罗（MC）传输代码的彻底调查显示了一个关键的错误。纠正的MC版本产生了现在在实验不确定性内的Sigma（rel）（z）值。特此沟通其他微量微量探测器。

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来源
《Physics in medicine and biology.》 |2016年第13期|共4页
作者
Villegas F.; Ahnesjo A.;
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作者单位

Uppsala Univ Med Radiat Phys Dept Immunol Genet &

Pathol Akad Sjukhuset SE-75185 Uppsala Sweden;

Uppsala Univ Med Radiat Phys Dept Immunol Genet &

Pathol Akad Sjukhuset SE-75185 Uppsala Sweden;

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原文格式 PDF
正文语种 eng
中图分类 R35;
关键词
microdosimetry; Monte Carlo simulations; microdosimetric spread;

机译：Microdosimetry;蒙特卡洛模拟;微透过蔓延;

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外文文献

1. Reply to the comment on 'Monte Carlo calculated microdosimetric spread for cell nucleus-sized targets exposed to brachytherapy I-125 and Ir-192 sources and Co-60 cell irradiation' [J] . Villegas F., Ahnesjo A. Physics in medicine and biology. . 2016,第13期

机译：对“蒙特卡洛针对暴露于近距离放射治疗I-125和Ir-192放射源以及Co-60细胞照射的细胞核大小靶标的微剂量计算的扩散”的评论回复
2. Reply to the comment on 'Monte Carlo calculated microdosimetric spread for cell nucleus-sized targets exposed to brachytherapy I-125 and Ir-192 sources and Co-60 cell irradiation' [J] . Villegas F., Ahnesjo A. Physics in medicine and biology. . 2016,第13期

机译：回复对'Monte Carlo计算的微透过差异的评论，用于细胞核尺寸的靶向暴露于近距离放射治疗I-125和IR-192来源和CO-60细胞照射'
3. Comment on 'Monte Carlo calculated microdosimetric spread for cell nucleus-sized targets exposed to brachytherapy (125)I and (192)Ir sources and (60)Co cell irradiation'. [J] . Lennart Lindborg, Jan Lillh?k, Jan-Erik Grindborg Physics in medicine and biology. . 2015,第21期

机译：评论“蒙特卡洛针对暴露于近距离放射治疗（125）I和（192）Ir来源和（60）Co细胞照射的细胞核大小靶标计算的微剂量分布”。
4. Monte Carlo Simulation of an Ir-192 Brachytherapy Source Spectra, Geometry and Anisotropy Factors Using Geant4 Code [C] . S. S. O. Fonseca-Rodrigues, M. Begalli, P. P. Queiroz Filho, IEEE Nuclear Science Symposium Conference . 2009

机译：Monte Carlo模拟IR-192近距离放射治疗源光谱，几何和各向异性因子使用GEANT4代码
5. Monte-Carlo dosimetry and real-time imaging of targeted irradiation consequences in 2-cell stage Caenorhabditis elegans embryo [O] . Eva Torfeh, Marina Simon, Giovanna Muggiolu, -1

机译：2细胞阶段秀丽隐杆线虫胚胎的靶向辐射后果的蒙特卡洛剂量测定和实时成像
6. EP-1478: Impact of the microdosimetric spread on LQ-parameterization of cell survival data for protons and Co-60 photons [O] . Villegas F., Bäckström G., Enger S.A., 2015

机译：EP-1478：微量剂量分布对质子和Co-60光子细胞存活数据的LQ参数化的影响

Reply to the comment on 'Monte Carlo calculated microdosimetric spread for cell nucleus-sized targets exposed to brachytherapy I-125 and Ir-192 sources and Co-60 cell irradiation'

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