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首页> 外文期刊>Physics in medicine and biology. >Direct impact analysis of multi-leaf collimator leaf position errors on dose distributions in volumetric modulated arc therapy: a pass rate calculation between measured planar doses with and without the position errors.
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Direct impact analysis of multi-leaf collimator leaf position errors on dose distributions in volumetric modulated arc therapy: a pass rate calculation between measured planar doses with and without the position errors.

机译:体积调制电弧疗法中剂量分布对多叶准直叶片位置误差的直接影响分析:测量平面剂量与位置误差的频率计算。

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摘要

We propose a new method for analyzing the direct impact of multi-leaf collimator (MLC) leaf position errors on dose distributions in volumetric modulated arc therapy (VMAT). The technique makes use of the following processes. Systematic leaf position errors are generated by directly changing a leaf offset in a linac controller; dose distributions are measured by a two-dimensional diode array; pass rates of the dose difference between measured planar doses with and without the position errors are calculated as a function of the leaf position error. Three different treatment planning systems (TPSs) were employed to create VMAT plans for five prostate cancer cases and the pass rates were compared between the TPSs under various leaf position errors. The impact of the leaf position errors on dose distributions depended upon the final optimization result from each TPS, which was explained by the correlation between the dose error and the average leaf gap width. The presented method determines leaf position tolerances for VMAT delivery for each TPS, which may facilitate establishing a VMAT quality assurance program in a radiotherapy facility.
机译:我们提出了一种新的方法,用于分析多叶子准直器(MLC)叶位置误差对体积调制电弧疗法(VMAT)的剂量分布的直接影响。该技术利用以下过程。通过直接改变LINAC控制器中的叶片偏移来产生系统叶位置误差;剂量分布由二维二极管阵列测量;测量平面剂量之间的剂量差异与具有位置误差之间的剂量差异的流速作为叶子位置误差的函数计算。采用三种不同的治疗计划系统(TPS)来创建五个前列腺癌病例的VMAT计划,并在各种叶子位置误差下比较TPS之间的通过率。叶子位置误差对剂量分布的影响依赖于每个TPS的最终优化结果,这是通过剂量误差和平均叶间隙宽度之间的相关性解释的。所提出的方法确定每个TPS的VMAT传送的叶子位置公差,这可以促进在放射治疗设施中建立VMAT质量保证程序。

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