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首页> 外文期刊>Physics in medicine and biology. >Investigating the impact of spatial priors on the performance of model-based IVUS elastography.
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Investigating the impact of spatial priors on the performance of model-based IVUS elastography.

机译：调查空间前方对基于模型的IVUS弹性术的影响。

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摘要

This paper describes methods that provide pre-requisite information for computing circumferential stress in modulus elastograms recovered from vascular tissue-information that could help cardiologists detect life-threatening plaques and predict their propensity to rupture. The modulus recovery process is an ill-posed problem; therefore, additional information is needed to provide useful elastograms. In this work, prior geometrical information was used to impose hard or soft constraints on the reconstruction process. We conducted simulation and phantom studies to evaluate and compare modulus elastograms computed with soft and hard constraints versus those computed without any prior information. The results revealed that (1) the contrast-to-noise ratio of modulus elastograms achieved using the soft prior and hard prior reconstruction methods exceeded those computed without any prior information; (2) the soft prior and hard prior reconstruction methods could tolerate up to 8% measurement noise, and (3) the performance of soft and hard prior modulus elastograms degraded when incomplete spatial priors were employed. This work demonstrates that including spatial priors in the reconstruction process should improve the performance of model-based elastography, and the soft prior approach should enhance the robustness of the reconstruction process to errors in the geometrical information.
机译：本文介绍了提供从血管组织信息中恢复的模量弹性图中计算圆周应力的先决条件的方法，这些信息可以帮助心脏病学家检测到危及生命的斑块并预测其破裂倾向。模量恢复过程是一个不良问题;因此，需要其他信息来提供有用的弹性图。在这项工作中，先前的几何信息用于对重建过程施加硬或软限制。我们进行了仿真和幻影研究，以评估和比较用软和硬度限制计算的模数弹性图与计算的模数弹性图，而没有任何事先信息。结果表明，使用软之前和硬之前的重建方法超过了没有任何事先的信息来计算实现（1）模量弹性图的对比度噪声比; （2）软效先前和硬现有的重建方法可耐受高达8％的测量噪声，并且（3）在采用不完全空间前沿时，软硬质量模量弹性图的性能降低。这项工作表明，包括重建过程中的空间前导者应提高基于模型的弹性造影的性能，软体的现有方法应增强重建过程对几何信息中的错误的鲁棒性。

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  • 来源
    《Physics in medicine and biology.》 |2011年第22期|共24页
  • 作者

    Richards MS; Doyley MM;

  • 作者单位

    Department of Electrical and Computer Engineering Hajim School of Engineering and Applied Sciences University of Rochester Hopeman Engineering Building Box 270126 Rochester NY 14627 USA.;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 R35;
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