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Therapeutic hypothermia after out-of hospital cardiac arrest: how to secure worldwide implementation.

机译:院外心脏骤停后的治疗性体温过低:如何确保在全球范围内实施。

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PURPOSE OF REVIEW: Despite the scientific evidence, therapeutic hypothermia in comatose out-of-hospital cardiac arrest survivors is still not widely used. It is unlikely that technical, logistical and financial barriers alone can explain the geographically large differences in its application. Our review focuses on how generic knowledge on implementation may help speed up the transfer of therapeutic hypothermia into daily practice. RECENT FINDINGS: In countries like Finland and Norway, rapid nationwide implementation has been obtained. Surveys from larger countries like the US, UK and Germany, however, show an overall low implementation rate of therapeutic hypothermia. Recent comparisons of outcome before and after implementation of therapeutic hypothermia in unselected groups of patients (effectiveness studies) show the same benefit as that found in previous randomized controlled trials (efficacy studies). New studies show that logistical, financial, technical and safety aspects cannot be considered barriers to the implementation of therapeutic hypothermia into daily practice. SUMMARY: More than 40 years after the late Peter Safar first suggested therapeutic hypothermia as standard therapy during postresuscitation care, worldwide implementation of this treatment seems possible. To secure this, however, hospitals and health systems must institute well defined implementation plans taking local cultural and organizational barriers into account.
机译:审查目的:尽管有科学证据,但昏迷性院外心脏骤停幸存者的治疗性低温治疗仍未广泛使用。仅凭技术,后勤和财务上的障碍就不可能解释其应用在地理上的巨大差异。我们的审查重点在于实施方面的一般知识如何帮助加快将治疗性低温疗法转化为日常实践的速度。最近的发现:在芬兰和挪威等国家,已在全国范围内迅速实施。但是,来自美国,英国和德国等较大国家的调查显示,治疗性体温疗法的总体实施率较低。未经选择的患者组在实施低温治疗前后的近期疗效比较(有效性研究)显示,其获益与以前的随机对照试验(功效研究)相同。新的研究表明,后勤,财务,技术和安全方面不能被视为在日常实践中实施治疗性低温治疗的障碍。摘要:在已故的彼得·萨法尔(Peter Safar)首次提出将治疗性体温过低作为复苏后护理期间的标准疗法后的40多年,这种疗法在全球范围内的实施似乎是可行的。但是,为了确保这一点,医院和卫生系统必须制定明确的实施计划,同时考虑到当地的文化和组织障碍。

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