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首页> 外文期刊>Current opinion in anaesthesiology >Oxygen in neonatal anesthesia: friend or foe?
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Oxygen in neonatal anesthesia: friend or foe?

机译：新生儿麻醉中的氧气：敌还是友？

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摘要

PURPOSE OF REVIEW: Clinical practices in oxygen administration are in need of change based on the increasing understanding of oxygen toxicity. Hypoxemia is due to many pathophysiological causes; avoiding hypoxemia is an important objective during neonatal anesthesia. Nevertheless, the only known cause for hyperoxemia is the excess and unnecessary administration of oxygen by healthcare providers. To avoid hyperoxemia is an important objective during neonatal anesthesia. RECENT FINDINGS: Neonatal exposure to 100% oxygen is almost never necessary. Much lower concentrations of inspired supplemental oxygen during the neonatal period can also lead to oxygen toxicity if oxygen is used when it is not necessary. Excess oxygen is associated with serious morbidities such as retinopathy of prematurity, bronchopulmonary dysplasia, injury to the developing brain, and childhood cancer. When providing supplemental oxygen, monitoring with modern SpO2 technology and avoidance of SpO2 values of 95-100% are less frequently associated with hyperoxemia. SUMMARY: Even brief neonatal exposures to pure oxygen must be avoided during neonatal anesthesia. When any dose of supplemental oxygen is given, a reliable pulse oximeter aiming to avoid hyperoxemia is necessary. Even though further research is essential, administration of oxygen by healthcare providers when it is not necessary is a foe and a neonatal health hazard.
机译：审查目的：基于对氧气毒性的日益了解，需要改变氧气管理的临床实践。低氧血症是由于许多病理生理原因引起的。避免低氧血症是新生儿麻醉期间的重要目标。然而，已知的高氧血症的唯一原因是医疗保健提供者过量和不必要的氧气管理。避免高氧血症是新生儿麻醉期间的重要目标。最近的发现：新生儿几乎不需要接触100％的氧气。如果在不必要时使用氧气，则新生儿期吸入的低得多的氧气浓度也会导致氧气中毒。过量的氧气与严重的疾病有关，例如早产儿视网膜病变，支气管肺发育不良，大脑发育受到损伤以及儿童癌症。当提供补充氧气时，采用现代SpO2技术进行监测并避免将SpO2值避免在95-100％时，高氧血症的发生频率降低。摘要：在新生儿麻醉期间，即使是短暂的新生儿纯氧暴露也必须避免。当给与任何剂量的补充氧气时，必须有一个可靠的脉搏血氧仪，以避免高氧血症。尽管必须进行进一步的研究，但在没有必要的情况下，由医疗保健提供者进行氧气管理是对敌人和新生儿健康的危害。

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