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首页> 外文期刊>Current opinion in anaesthesiology >Perioperative coagulation management in the intensive care unit
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Perioperative coagulation management in the intensive care unit

机译：重症监护室围手术期凝血管理

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PURPOSE OF REVIEW: Coagulopathy in an ICU setting is multifactorial, but newer anticoagulation agents are the potentially contributing causes. Critically ill patients may suffer from disorders because of surgery or trauma, in addition to acquired causes including antiplatelet agents and the new oral anticoagulants. An understanding of the coagulopathy, hemostatic considerations, and therapeutic approaches is important when managing these patients. RECENT FINDINGS: All anticoagulation agents may contribute to coagulopathy in critically ill patients. Options for management include hemodialysis, transfusion of blood products, and prohemostatic drugs. Recombinant and purified coagulation therapies are also now available in most countries that provide clinicians with specific agents to treat targeted deficiencies. SUMMARY: Coagulopathy occurs in ICU patients because of multiple factors including anticoagulants, dilution, fibrinolysis, and factor consumption. Therapeutic prohemostatic pharmacologic approaches, in addition to standard transfusion therapy, need to be considered in managing coagulopathy in the ICU setting.
机译：审查目的：ICU中的凝结病是多因素的，但较新的抗凝剂是潜在的病因。重症患者可能会因手术或创伤而遭受疾病困扰，此外还有获得性病因，包括抗血小板药和新型口服抗凝药。在管理这些患者时，了解凝血病，止血注意事项和治疗方法很重要。最新发现：所有抗凝剂均可能导致危重患者的凝血病。管理的选项包括血液透析，血液制品输注和止血药。现在，大多数国家还提供重组和纯化的凝血疗法，为临床医生提供治疗目标缺陷的特异性药物。摘要：由于多种因素（包括抗凝剂，稀释，纤维蛋白溶解和因素消耗），导致ICU患者发生凝结病。在ICU中，除了标准的输血疗法外，还应考虑使用止血药治疗方法。

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