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Optimal perioperative oxygen administration.

机译:围手术期最佳输氧。

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PURPOSE OF REVIEW: During anesthesia and surgery oxygen is routinely administered to all patients. Inspired oxygen concentrations, however, vary between 30 and 100%, and oxygen is often administered in a seemingly random manner. During the last decade it has been shown in several randomized trials that perioperative supplemental oxygen administration might improve outcome after certain surgical procedures. The purpose of this review is to provide an overview about the benefits and risks of supplemental oxygen administration in the perioperative period. RECENT FINDINGS: Supplemental oxygen improves immune function. Furthermore, 80% inspired oxygen fraction almost doubles subcutaneous tissue oxygen tension and halves the rate of postoperative wound infections. Some studies have shown that supplemental oxygen also decreases the rate of postoperative nausea and vomiting after laparoscopic and open abdominal surgical procedures. Preconditioning with oxygen might improve organ function after liver transplantation and outcome after spinal ischemic insults. Supplemental perioperative oxygen administration is not associated with clinically important side effects. SUMMARY: Supplemental oxygen administration during the perioperative period might be a simple, inexpensive and well-tolerated treatment option to improve patient outcome. The optimal inspired oxygen concentration still needs to be evaluated.
机译:审查目的:在麻醉和手术期间,常规向所有患者施用氧气。但是,吸入的氧气浓度在30%至100%之间变化,并且氧气通常以看似随机的方式给药。在过去的十年中,一些随机试验表明围手术期补充氧气可以改善某些外科手术后的结局。这篇综述的目的是概述围手术期补充氧气的益处和风险。最新发现:补充氧气可改善免疫功能。此外,80%的吸氧分数几乎使皮下组织的氧气张力增加了一倍,并使术后伤口感染的速度减半。一些研究表明,在腹腔镜和开腹手术后,补充氧气还可以降低术后恶心和呕吐的发生率。氧气预处理可能会改善肝移植后的器官功能和脊髓缺血性损伤后的预后。围手术期补充氧气与临床上重要的副作用无关。摘要:围手术期补充氧气可能是一种简单,便宜且耐受性良好的治疗方案,可改善患者预后。最佳吸入氧气浓度仍需要评估。

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