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Endoscopic Approaches for Early-Stage Esophageal Cancer: Current Options

机译:早期食管癌的内镜治疗方法:当前选择

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Early esophageal cancer is confined to the mucosa or submucosa of the esophagus. While most esophageal cancer is detected at an advanced stage (requiring surgical resection, chemotherapy, and radiation), early-stage mucosal lesions may be detected through Barrett's surveillance programs or incidentally on diagnostic upper endoscopies performed for other reasons. These early-stage cancers are often amenable to endoscopic therapies, including mucosal resection, ablation, and cryotherapy. Studies suggest equivalent survival rates and reduced morbidity but higher recurrence rates with endoscopic removal of early-stage cancers compared to surgical resection. There is emerging data regarding the efficacy and long-term outcomes of endoscopic therapy for early esophageal cancer that is promising, and further research is needed to better define the role of endoscopic therapy in the management of early esophageal cancer.
机译:早期的食道癌局限于食道的粘膜或粘膜下层。虽然大多数食道癌是在晚期(需要手术切除,化学疗法和放射线)检出的,但早期粘膜病变可通过Barrett的监视程序或偶然因其他原因进行的诊断性内镜检查来检出。这些早期癌症通常适合内窥镜治疗,包括粘膜切除,消融和冷冻治疗。研究表明,与手术切除相比,内镜切除早期癌症的生存率和发病率降低,但复发率更高。关于内镜治疗早期食管癌的疗效和长期结果的新兴数据令人鼓舞,需要进一步研究以更好地界定内镜治疗在食管癌早期治疗中的作用。

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