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首页> 外文期刊>Physics of fluids >Particle and rigidized red blood cell concentration distributions in microchannel flows
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Particle and rigidized red blood cell concentration distributions in microchannel flows

机译：微通道流动中的粒子和刚性的红细胞浓度分布

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摘要

The motion and concentration distribution of particles and cells in flow are important factors which affect the fluid properties, flow structure, and mass transfer of biological and chemical species in blood vessels and channels. In this study, number density distributions of particles and rigidized red blood cells (RBCs) in a microchannel whose size is comparable to the sizes of the particle and RBCs are measured. Measurements were conducted at several streamwise locations for suspensions of particles and RBCs with hematocrits of the order of 10% and particle sizes of 5 and 8 mu m. Analysis of the migration and resulting concentration distribution of the particles and RBCs was conducted using a model that considers the particle-particle collision and fluid dynamic force. As the size of the microchannel is small, the wall effect on the collision and migration of the particles and RBCs was significant. The wall reduced the overlapping area of the particles in collision and their displacement after collision (mobility), which varied the number, location, and magnitude of the maximum peaks observed in the number density distribution. Furthermore, the rotational motion of the rigidized RBCs in the channel flow reduced the effective lengths of the overlapping area and displacement, whereas it produced additional migration at the wall. With these terms added in the model, the number density distributions of the particles and RBCs showed reasonable agreement with those of the measurement. Especially, the number of peaks and their location for the maximum values in the model and measurement matched well. Published under license by AIP Publishing.
机译：流动中颗粒和细胞的运动和浓度分布是影响血管和通道中生物和化学物质的流体性质，流动结构和传质的重要因素。在该研究中，测量尺寸与颗粒和RBCs尺寸相当的微通道中颗粒和刚性的红细胞（RBC）的数量密度分布。在几个流动的位置进行测量，用于颗粒和RBC的悬浮液，其血细胞种植体为10％和颗粒尺寸为5和8μm。使用考虑粒子颗粒碰撞和流体动力力的模型进行迁移和RBCs的迁移和RBC的浓度分布。随着微通道的尺寸很小，墙壁对颗粒和RBCs的碰撞和迁移是显着的。壁在碰撞中缩小颗粒的重叠区域及其在碰撞（移动性）之后的位移，其在数量密度分布中观察到的最大峰的数量，位置和大小。此外，沟道流中的刚性RBC的旋转运动降低了重叠区域和位移的有效长度，而它在壁上产生了额外的迁移。利用这些术语在模型中添加，粒子和RBC的数量分布显示与测量值合理的协议。特别是，模型和测量中最大值的峰值数及其位置匹配良好。通过AIP发布在许可证下发布。

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