Human oncogenic viruses and cancer

Ahuja Richa; Jamal Azfar; Nosrati Nagisa; Pandey Vijaya; Rajput Pallavi; Saxena Nehul; Sidhu Kaveri; Kumar Vijay

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Human oncogenic viruses and cancer

机译：人致癌病毒和癌症

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The role of viral infection in cancer was established towards the beginning of 20th century. The study of tumour viruses, their oncogenes and different mechanisms employed by these viruses to subvert the growth-suppressive and pro-apoptotic functions of host tumour suppressor genes has laid the foundation of cancer biology. The human tumour viruses induce malignancies after a prolonged latency and in conjunction with other environmental and host factors. The eight known human tumour viruses contribute to nearly 10-15% of the cancers worldwide. Advancements in research on virus-related cancers offer a plethora of opportunities to fight cancer by preventing viral spread through vaccination and use of antivirals. Besides, recent developments on viral oncogenic mechanisms should allow development of novel and targeted approaches for control and treatment of virus-associated human cancers.

机译：病毒感染在癌症中的作用已确立到20世纪初。对肿瘤病毒，其致癌基因以及这些病毒用来破坏宿主抑癌基因的生长抑制和促凋亡功能的不同机制的研究奠定了癌症生物学的基础。人肿瘤病毒在潜伏期延长后并与其他环境和宿主因素一起诱发恶性肿瘤。八种已知的人类肿瘤病毒占全世界癌症的近10-15％。病毒相关癌症的研究进展为通过预防接种和使用抗病毒药物传播病毒提供了许多与癌症作斗争的机会。此外，病毒致癌机制的最新发展应允许开发新颖的靶向方法来控制和治疗病毒相关的人类癌症。

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来源
《Current Science: A Fortnightly Journal of Research》 |2014年第5期|共18页
作者
Ahuja Richa; Jamal Azfar; Nosrati Nagisa; Pandey Vijaya; Rajput Pallavi; Saxena Nehul; Sidhu Kaveri; Kumar Vijay;
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正文语种 eng
中图分类自然科学现状及发展;
关键词
Cancer; cell transformation; mitogenic signalling; tumour virus; viral integration;

机译：癌症;细胞转化;有丝分裂信号;肿瘤病毒;病毒整合;

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1. Oncogenic virus-mediated cell fusion: new insights into initiation and progression of oncogenic viruses--related cancers. [J] . Gao P, Zheng J Cancer letters . 2011,第1期

机译：致癌病毒介导的细胞融合：对致癌病毒相关癌症的发生和发展的新见解。
2. Investigation of three oncogenic epitheliotropic viruses shows human papillomavirus in association with non-melanoma skin cancer [J] . Baez Camila Freze, Venceslau Goncalves Marianna Tavares, da Rocha Willker Menezes, European journal of clinical microbiology and infectious diseases: Official publication of the European Society of Clinical Microbiology . 2019,第6期

机译：三种致癌性上皮病毒的研究显示了与非黑色素瘤皮肤癌相关联的人乳头瘤病毒
3. Oncogenic Viruses and Breast Cancer: Mouse Mammary Tumor Virus (MMTV), Bovine Leukemia Virus (BLV), Human Papilloma Virus (HPV), and Epstein–Barr Virus (EBV) [J] . James S. Lawson, Brian Salmons, Wendy K. Glenn Frontiers in Oncology . 2018,第6期

机译：致癌病毒和乳腺癌：小鼠乳腺肿瘤病毒（MMTV），牛白血病病毒（BLV），人乳头瘤病毒（HPV）和爱泼斯坦-巴尔病毒（EBV）
4. A novel scoring estimator to screening for oncogenic chimeric transcripts in cancer transcriptome sequencing [C] . Jian-lei Gu, Yao Lu, Shi-yi Liu, IEEE International Conference on Bioinformatics and Biomedicine . 2016

机译：一种在癌症转录组测序中筛选致癌嵌合转录本的新型评分估算器
5. Association between lung cancer/multiple myeloma mortality and exposure to oncogenic viruses -- statistical analyses using non-model- and model-based statistical methods and various control sampling schemes for cancer mortality in occupational cohorts. [D] . Ndetan, Harrison Tatandam. 2009

机译：肺癌/多发性骨髓瘤死亡率与致癌病毒暴露之间的关联-使用非基于模型和基于模型的统计方法以及各种对照抽样方案对职业人群的癌症死亡率进行统计分析。
6. Regulation of Autophagy in Cells Infected With Oncogenic Human Viruses and Its Impact on Cancer Development [O] . Tiziana Vescovo, Benedetta Pagni, Mauro Piacentini, 2020

机译：自噬在感染致癌人类病毒的细胞中的调控及其对癌症发展的影响
7. Going viral? Linking the etiology of human prostate cancer to the PCA 3 long noncoding RNA and oncogenic viruses [O] . Andre A Teixeira, Serena Marchiò, Emmanuel Dias‐Neto, 2017

机译：去病毒吗？将人前列腺癌的病因与PCA 3长的非加入RNA和致癌病毒联系起来
8. Cancer Risk in Workers Exposed to Oncogenic Viruses [R] . Johnson, E. S., Felini, M. 2008

机译：暴露于致癌病毒的工人的癌症风险

Human oncogenic viruses and cancer

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