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Screening and isolation of cyclosporine-related compound producing soil fungi from the Western Ghats, Tamil Nadu

机译:泰米尔纳德邦西高止山脉的环孢素相关化合物生产土壤真菌的筛选和分离

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摘要

The fungal kingdom has enormous biodiversity, with around 70,000 known species and an estimated total of about 1.5 million species, presenting a wide scope for further research. The fungal species are known for the production of enzymes and secondarymetabolites, which have not been exploited completely. The best-known fungal secondary metabolites that are subjected to commercial production are the bate-lactam antibiotics. The fungal genus Tolypocladium, first described by Gams in 1971, encompasses fungi imper-fecti occurring in soil or litter habitats. This species is well characterized by white, hyaline or bright coloured, relatively slow-growing cottony colonies1'2.
机译:真菌王国具有巨大的生物多样性,大约有70,000种已知物种,估计总数约为150万种,为进一步研究提供了广阔的空间。已知真菌种类可产生酶和次级代谢产物,尚未完全开发利用。商业化生产的最著名的真菌次生代谢产物是贝特-内酰胺类抗生素。真菌属Tolypocladium,最早由Gams在1971年描述,涵盖了存在于土壤或垃圾栖息地中的抗病真菌。该物种的特征是白色,透明或明亮,生长较慢的棉质菌落1'2。

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