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首页> 外文期刊>Current Science: A Fortnightly Journal of Research >Efficacy and safety of herbal spermicidal contraceptive, Consap
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Efficacy and safety of herbal spermicidal contraceptive, Consap

机译：草药杀精剂避孕药的功效和安全性

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摘要

Consap is a locally acting, non-hormonal, herbal spermicidal contraceptive isolated from Sapindus mukor-osii. It has been observed to be free from systemic side-effects such as nausea, vomiting and irregularities in the menstrual cycle. It is a woman-controlled reversible method which needs to be used before intercourse. It has additional antitrichomonas activity and is more vaginal-friendly. In the present study, 521 women volunteers in the reproductive age group have been screened at six centres. Of these, 470 were included in the trial covering 2076 months of Consap cream use with 2358 total cycles covered during the study. Out of a total, 324 cases who used this cream for at least 6 months and more were considered to have completed the trial. Inthis study only nine patient failures and four method failure pregnancies resulted with a Pearl index of 2.3, which is acceptable for the general population. This study thus shows that Consap cream when used as prescribed is an effective contraceptive.It is a good alternative for women who do not want to use oral contraceptive pills or intrauterine devices.
机译：Consap是一种从Sapindus mukor-osii中分离出来的局部作用的非激素草药杀精子避孕药。据观察，它没有诸如月经周期中的恶心，呕吐和不规则等全身性副作用。这是一种由女性控制的可逆方法，需要在性交之前使用。它具有额外的抗毛滴虫活性，对阴道更友好。在本研究中，已经在六个中心对521岁育龄女性志愿者进行了筛查。其中有470例被纳入试验，涵盖了2076个月的Consap乳膏使用，研究期间总共进行了2358个周期。在总共324例使用这种乳膏至少6个月或更长时间的病例中，被认为已完成试验。在这项研究中，只有9例患者失败和4例方法失败怀孕，Pearl指数为2.3，这对于一般人群来说是可以接受的。因此，这项研究表明Consap乳膏按处方使用是有效的避孕药，对于不想使用口服避孕药或宫内节育器的女性来说，它是一个很好的选择。

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