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Hypertension epidemiology in India: lessons from Jaipur Heart Watch

机译:印度高血压流行病学:斋浦尔心脏观察的教训

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Cardiovascular diseases have emerged as an important health problem in India. High blood pressure (BP) is a major risk factor and better control can lead to prevention of 300,000 of the 1.5 million annual deaths from cardiovascular diseases in India. Epidemiological studies demonstrate that prevalence of hypertension is increasing rapidly among Indian urban populations and using the current definitions more than two-fifths of the Indian urban adult population has hypertension. The prevalence is lower in rural populations, but is increasing. Jaipur Heart Watch (JHW) is an ongoing cross-sectional epidemiological study in western India. Successive studies have been performed in rural (JHW-R, 1992-93) and urban locations (JHW-1, 1993-94; JHW-2, 1999-2000; JHW-3, 2002-03, and JHW-4, 2004-05). The studies evaluated adults >= 20 years using standardized methodology and in the present analyses subjects aged 20-59 years from these JHW studies [4102 men (1700, 1294, 469, 179 and 413) and 2872 women (1063, 655, 486, 195 and 433)] have been included. Prevalence of various cardio-vascular risk factors: smoking/tobacco use, sedentary habits, overweight/obesity (body mass index >= 25 kg/m(2)), central obesity (waist : hip ratio > 0.95 men, > 0.85 women), hypertension, dyslipidemias, metabolic syndrome and diabetes was determined. Trends were analysed using least squares linear analyses. Results show that mean systolic BP increased with age in all the study cohorts, while there was no significant difference in diastolic BP. Age-adjusted prevalence of hypertension in JHW-R, JHW-1, JHW-2, JHW-3 and JHW-4 studies in men was 21.6, 29.1, 29.6, 42.5 and 45.1% and in women it was 15.7, 21.7, 25.5, 35.2 and 38.2% (P for trend < 0.05). There was a significant association of escalating hypertension with obesity and truncal obesity in both men (two-line regression analysis, unadjusted r(2) = 0.91 and 0.50 respectively) and women (r(2) = 0.88 and 0.57; P < 0.05). Increasing hypertension in India is related to increasing adiposity levels. Population and individual-based measures to prevent and control high BP should focus on measures to prevent obesity.
机译:在印度,心血管疾病已成为重要的健康问题。高血压(BP)是主要的危险因素,如果控制得当,可以预防印度每年150万人死于心血管疾病的30万人。流行病学研究表明,在印度城市人口中,高血压的患病率正在迅速增加,按照目前的定义,超过五分之二的印度城市成年人口患有高血压。农村人口患病率较低,但正在增加。斋浦尔心脏观察(JHW)是印度西部正在进行的横断面流行病学研究。已在农村地区(JHW-R,1992-93)和城市地区(JHW-1,1993-94; JHW-2,1999-2000; JHW-3,2002-03和JHW-4,2004)进行了连续研究-05)。该研究使用标准化方法对> = 20岁的成年人进行了评估,在本次分析中,这些JHW研究中年龄在20-59岁之间的受试者[4102名男性(1700、1294、469、179和413)和2872女性(1063、655、486, 195和433)]已包括在内。各种心血管疾病危险因素的流行:吸烟/吸烟,久坐的习惯,超重/肥胖(体重指数> = 25 kg / m(2)),中枢性肥胖(腰围:髋部比例> 0.95男性,> 0.85女性)确定了高血压,血脂异常,代谢综合征和糖尿病。使用最小二乘线性分析来分析趋势。结果显示,所有研究队列的平均收缩压均随年龄增加,而舒张压无明显差异。 JHW-R,JHW-1,JHW-2,JHW-3和JHW-4研究中按年龄调整的高血压患病率,男性为2​​1.6%,29.1%,29.6%,42.5%和45.1%,女性为15.7%,21.7%,25.5% ,35.2和38.2%(趋势<0.05的P)。男性(两线回归分析,未经调整的r(2)= 0.91和0.50)和女性(r(2)= 0.88和0.57; P <0.05)的高血压升级与肥胖和截断性肥胖之间存在显着关联。 。印度高血压的增加与肥胖程度的增加有关。基于人群和个体的预防和控制高血压的措施应集中于预防肥胖的措施。

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