Nanowire Analysis of Cancer-Testis Antigens as Biomarkers of Aggressive Prostate Cancer

Takahashi Sayuri; Shiraishi Takumi; Miles Nancy; Trock Bruce J.; Kulkarni Prakash; Getzenberg Robert H.

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Nanowire Analysis of Cancer-Testis Antigens as Biomarkers of Aggressive Prostate Cancer

机译：纳米线分析癌症 - 睾丸抗原作为侵袭性前列腺癌的生物标志物

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OBJECTIVE To demonstrate the ability of the nCounter Analysis System, a nanowire technology, to sensitively and accurately detect cancer-testis antigens (CTAs) in men with prostate cancer and correlate them with disease parameters. The clinical implementation of novel biomarkers is necessary to provide for individual disease treatment planning for men with prostate cancer. The CTAs, as cancer-associated biomarkers that may correlate with aggressive disease, have the potential to play an important role.

机译：目的展示NCounter分析系统，纳米线技术，敏感和准确地检测具有前列腺癌的男性癌症抗原（CTA）的能力，并将它们与疾病参数相关联。新型生物标志物的临床实施是为前列腺癌的男性的个体疾病治疗计划提供必要的。作为可能与侵袭性疾病相关的癌症相关生物标志物的CTA有可能发挥重要作用。

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《Urology》 |2015年第3期|共7页
作者
Takahashi Sayuri; Shiraishi Takumi; Miles Nancy; Trock Bruce J.; Kulkarni Prakash; Getzenberg Robert H.;
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GTx Inc 175 Toyota Plaza 7th Floor Memphis TN 38103 USA;

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正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病）;
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专利

1. 癌症／睾丸抗原：识别侵袭性和非侵袭性前列腺癌的新工具 [J] . Takumi Shiraishi, Robert H Getzenberg, Prakash Kulkarni 亚洲男性学杂志：英文版 . 2012,第003期
2. Nanowire Analysis of Cancer-Testis Antigens as Biomarkers of Aggressive Prostate Cancer [J] . Takahashi Sayuri, Shiraishi Takumi, Miles Nancy, Urology . 2015,第3期

机译：纳米线分析癌症 - 睾丸抗原作为侵袭性前列腺癌的生物标志物
3. Investigation on core-fucosylated prostate-specific antigen as a refined biomarker for differentiation of benign prostate hyperplasia and prostate cancer of different aggressiveness [J] . Robert Lang, Vinzent Rolny, Andreas Leinenbach, Tumour biology : . 2019,第3期

机译：核心岩藻糖基化前列腺特异性抗原作为区分良性前列腺增生和不同侵袭性前列腺癌的生物标志物的研究
4. Cancer-testis antigens: Unique cancer stem cell biomarkers and targets for cancer therapy [J] . Gordeeva Olga Seminars in cancer biology . 2018,第期

机译：癌症睾丸抗原：独特的癌症干细胞生物标志物和癌症治疗的靶标
5. Development of In Vitro Prostate Cancer Biomarkers on the Basis of Gelatin Matrix Incorporated Gold Nanoparticles Functionalized with Fluorescence Dye and Prostate Specific Membrane Antigen [C] . K. CHUBINIDZE, B. PARTSVANIA, A. KHUSKIVADZE, International Caucasian Symposium on Polymers and Advanced Materials . 2020

机译：基于明胶基质的体外前列腺癌生物标志物的发展掺入了用荧光染料和前列腺特异性膜抗原官能化的金纳米颗粒
6. Evaluating the SSX family of cancer-testis antigens as immunological targets for the treatment of prostate cancer. [D] . Smith, Heath. 2012

机译：评估SSX家族的癌症-睾丸抗原作为治疗前列腺癌的免疫学靶标。
7. Nanowire Analysis of Cancer-Testis Antigens as Biomarkers of Aggressive Prostate Cancer [O] . Sayuri Takahashi, Takumi Shiraishi, Nancy Miles, -1

机译：癌症睾丸抗原的纳米线分析作为侵略性前列腺癌的生物标志物
8. Nanowire Analysis of Cancer-Testis Antigens as Biomarkers of Aggressive Prostate Cancer [O] . Sayuri Takahashi, Takumi Shiraishi, Nancy Miles, 2015

机译：纳米线分析癌症 - 睾丸抗原作为侵袭性前列腺癌的生物标志物
9. Multiplex Cancer/Testis Antigen-Based Biomarker Panel to Predict the Aggressive Phenotype of Prostate Cancer. [R] . Veltri, R. W. 2016

机译：基于多重癌症/睾丸抗原的生物标志物小组预测前列腺癌的侵略性表型。

Nanowire Analysis of Cancer-Testis Antigens as Biomarkers of Aggressive Prostate Cancer

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