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首页> 外文期刊>Current Science: A Fortnightly Journal of Research >Innate immune responses in families of Indian major carp, Labeo rohita, differing in their resistance to Edwardsiella tarda infection
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Innate immune responses in families of Indian major carp, Labeo rohita, differing in their resistance to Edwardsiella tarda infection

机译：印度主要鲤鱼Labeo rohita的先天免疫应答，其对爱德华氏菌感染的抵抗力不同

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摘要

Genetic variation in the innate immune responses of Indian major carp, rohu (Labeo rohita) families was investigated. Innate immune responses were measured among the fullsib families of rohu, produced using nested mating design for increased growth. Significant differences as well as large variations in each of the immune parameters were observed. The natural resistance of each family to Edwardsiella tarda infection was also assessed by intraperitoneal challenge study. A wide variation in per cent survival (0 to 100) was noticed among the families after bacterial challenge. A positive significant (P < 0.05) correlation was observed between per cent survival and superoxide production as measured through nitroblue tetrazolium assay. On the other hand, no significant correlation was observed between other immune parameters, viz. serum lysozyme activity, serum myeloperoxidase content, plasma glucose content, serum haemolysin, haemagglutination and bacterial agglutination titres measured and the per cent survival.
机译：研究了印度主要鲤鱼（Labeo rohita）家族的先天免疫应答的遗传变异。使用巢状交配设计以提高生长速度，在六hu的同胞家族中测量先天免疫应答。观察到每个免疫参数的显着差异以及较大差异。还通过腹膜内攻击研究评估了每个家庭对塔氏爱德华氏菌感染的天然抗性。细菌攻击后，各家庭的存活率差异很大（0到100）。通过硝基蓝四唑鎓测定法测得的存活率和超氧化物产生之间存在正相关（P <0.05）。另一方面，未观察到其他免疫参数之间的显着相关性。测定血清溶菌酶活性，血清髓过氧化物酶含量，血浆葡萄糖含量，血清溶血素，血细胞凝集和细菌凝集滴度，以及存活百分率。

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