...
首页> 外文期刊>The FEBS journal >Is nicotine exposure linked to cardiopulmonary vulnerability to COVID-19 in the general population?
【24h】

Is nicotine exposure linked to cardiopulmonary vulnerability to COVID-19 in the general population?

机译:尼古丁暴露是否与一般人群中的Covid-19有群脆弱性有关?

获取原文
获取原文并翻译 | 示例
           

摘要

The recent emergence of COVID-19 has resulted in a worldwide crisis, with large populations locked down and transportation links severed. While approximately 80% of infected individuals have minimal symptoms, around 15-20% need to be hospitalized, greatly stressing global healthcare systems. As of March 10, the death rate appears to be about 3.4%, although this number is highly stratified among different populations. Here, we focus on those individuals who have been exposed to nicotine prior to their exposure to the virus. We predict that these individuals are 'primed' to be at higher risk because nicotine can directly impact the putative receptor for the virus (ACE2) and lead to deleterious signaling in lung epithelial cells.
机译:最近的Covid-19出现导致了全球危机,大型人口锁定和交通连接。 虽然大约80%的受感染的个体具有最小的症状,但大约15-20%需要住院,大大强调全球医疗保健系统。 截至3月10日,死亡率似乎约为3.4%,尽管该号码在不同种群之间具有高度分层。 在这里,我们专注于在暴露于病毒之前暴露于尼古丁的人。 我们预测,这些个体是“灌注”的风险更高,因为尼古丁可以直接影响病毒(ACE2)的推定受体,并导致肺上皮细胞中的有害信号传导。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号