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Altitude illness: update on prevention and treatment.

机译:高原病:最新的预防和治疗。

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ABSTRACT: Altitude illness is a broad category of disease encompassing acute mountain sickness (AMS), high-altitude cerebral edema (HACE), and high-altitude pulmonary edema (HAPE) that can affect persons who travel to altitude without adequate acclimatization. Initial symptoms of AMS and the more serious HACE or HAPE can be subtle, and it is important that the practitioner be able to recognize and differentiate between these diagnoses because they can progress rapidly and be fatal if untreated. There are well-established criteria and many proven therapies both for prophylaxis and treatment of altitude illness; however, despite intense research efforts, the specific mechanisms of these complex diseases remain elusive. Adequate acclimatization via controlled ascent remains the most important factor in preventing altitude illness, although prophylactic pharmacotherapy also may be useful. Rapid descent remains the most important treatment factor, although treatment at altitude with various therapies is possible for mild cases with adequate resources.
机译:摘要:高原病是一类广泛的疾病,包括急性高山病(AMS),高海拔脑水肿(HACE)和高海拔肺水肿(HAPE),它们会影响到没有充分适应环境的人。 AMS和更严重的HACE或HAPE的初始症状可能很细微,从业人员能够识别并区分这些诊断很重要,因为它们可以迅速发展,如果不加以治疗会致命。预防和治疗高原病有完善的标准和许多行之有效的疗法。然而,尽管进行了深入的研究,但这些复杂疾病的具体机制仍然难以捉摸。尽管预防性药物治疗也可能有用,但通过控制上升进行的充分适应仍是预防高原病的最重要因素。快速下降仍然是最重要的治疗因素,尽管对于有足够资源的轻度病例,可以在高原上进行多种治疗。

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