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Association of Mycobacterium paratuberculosis in Crohn's disease and Johne's disease: A possible zoonotic threat [Review]

机译:结核分支杆菌与克罗恩病和约翰氏病的关联:可能的人畜共患病威胁[综述]

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摘要

Mycobacterium paratuberculosis is the well-known etiologic agent of Johne's disease (JD), of the ruminants, In recent years, this organism has drawn attention due to its possible role in Crohn's disease (CD), a chronic inflammatory bowel disease of the human gastrointestinal tract. But the growing concern over the zoonotic potential of M. paratuberculosis is still not well established. The possible association of M, paratuberculosis with CD and its zoonotic significance has been reviewed in the light of isolation studies, experimental disease production, histopathological and immunological evidences, besides DNA sequence analysis. Food-borne exposure, the possible source of human infection, has also been discussed. [References: 74]
机译:副结核分枝杆菌是反刍动物约翰德氏病(JD)的著名病因道。但是,对副结核分枝杆菌的人畜共患病潜力的日益增长的关注仍未得到充分确定。除DNA序列分析外,还根据分离研究,实验疾病产生,组织病理学和免疫学证据,回顾了M,副结核病与CD的可能关联及其人畜共患病意义。还讨论了食源性暴露,这是人类感染的可能来源。 [参考:74]

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