Fisetin attenuates melanoma growth and tumorigenicity by downregulating PI3K/MAPK signaling and disrupting eIF4F complex

de Oca M. Montes; Sharma P.; Pearlman R.; Pal H.; Afaq F.

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Fisetin attenuates melanoma growth and tumorigenicity by downregulating PI3K/MAPK signaling and disrupting eIF4F complex

机译：通过下调PI3K / MAPK信号传导和破坏EIF4F复合物来衰减黑色素瘤生长和肿瘤性

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来源
《The Journal of investigative dermatology.》 |2018年第19期|共1页
作者
de Oca M. Montes; Sharma P.; Pearlman R.; Pal H.; Afaq F.;
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作者单位

UAB Dept Dermatol Greenville SC USA;

UAB Dept Dermatol Birmingham AL USA;

UAB Dept Dermatol Birmingham AL USA;

UAB Dept Dermatol Birmingham AL USA;

UAB Dept Dermatol Birmingham AL USA;

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原文格式 PDF
正文语种 eng
中图分类皮肤病学与性病学;
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1. Fisetin attenuates melanoma growth and tumorigenicity by downregulating PI3K/MAPK signaling and disrupting eIF4F complex [J] . de Oca M. Montes, Sharma P., Pearlman R., The Journal of investigative dermatology. . 2018,第5a19期

机译：通过下调PI3K / MAPK信号传导和破坏EIF4F复合物来衰减黑色素瘤生长和肿瘤性
2. Inhibition of human melanoma cell growth by the dietary flavonoid fisetin is associated with disruption of Wnt/beta-catenin signaling and decreased Mitf levels. [J] . Syed DN, Afaq F, Maddodi N, The Journal of investigative dermatology. . 2011,第6期

机译：饮食类黄酮类非瑟酮抑制人黑素瘤细胞的生长与Wnt /β-catenin信号的破坏和Mitf水平降低有关。
3. Involvement of PI3K and MAPK signaling in bcl-2-induced vascular endothelial growth factor expression in melanoma cells [J] . Trisciuoglio D, Iervolino A, Zupi G, Molecular biology of the cell . 2005,第9期

机译：PI3K和MAPK信号通路参与bcl-2诱导的黑色素瘤细胞中血管内皮生长因子的表达
4. Modeling PI3K/PDK1/Akt and MAPK Signaling Pathways Using Continuous Petri Nets [C] . Giulia Russo, Marzio Pennisi, Roberta Boscarino, International conference on intelligent computing . 2017

机译：使用连续Petri网建模PI3K / PDK1 / Akt和MAPK信号通路
5. Molecular biology of melanoma growth stimulatory activity (MGSA): Molecular cloning, eukaryotic expression, partial exploration of signal transduction mechanism, and evaluation of tumorigenic potential [D] . Balentien, Eddy Genaro 1990

机译：黑色素瘤生长刺激活性（MGSA）的分子生物学：分子克隆，真核表达，信号转导机制的部分探索以及致瘤潜力的评估
6. SBI-0640756 attenuates the growth of clinically unresponsive melanomas by disrupting the eIF4F translation initiation complex [O] . Yongmei Feng, Anthony B. Pinkerton, Laura Hulea, -1

机译：SBI-0640756通过破坏eIF4F翻译起始复合物来减弱临床无反应的黑色素瘤的生长
7. Inhibition of Human Melanoma Cell Growth by the Dietary Flavonoid Fisetin Is Associated with Disruption of Wnt/β-Catenin Signaling and Decreased Mitf Levels [O] . Syed Deeba N., Afaq Farrukh, Maddodi Nityanand, 2011

机译：饮食类黄酮类非瑟酮抑制人黑素瘤细胞生长与Wnt /β-Catenin信号转导和Mitf水平降低有关

Fisetin attenuates melanoma growth and tumorigenicity by downregulating PI3K/MAPK signaling and disrupting eIF4F complex

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